ID B6VMT0_PHOAA Unreviewed; 491 AA. AC B6VMT0; C7BNK7; DT 16-DEC-2008, integrated into UniProtKB/TrEMBL. DT 16-DEC-2008, sequence version 1. DT 15-FEB-2017, entry version 62. DE SubName: Full=Succinate-semialdehyde dehydrogenase, nadp-dependent activit (Succinate-semialdehyde dehydrogenase) {ECO:0000313|EMBL:CAQ83019.1}; DE SubName: Full=Succinate-semialdehyde dehydrogenase,nadp-dependent activit (Succinate-semialdehyde dehydrogenase) {ECO:0000313|EMBL:CAR67460.1}; GN Name=gabD {ECO:0000313|EMBL:CAR67460.1}; GN OrderedLocusNames=PAU_00927 {ECO:0000313|EMBL:CAQ83019.1}; GN ORFNames=PA-RVA14-1084 {ECO:0000313|EMBL:CAR67460.1}; OS Photorhabdus asymbiotica subsp. asymbiotica (strain ATCC 43949 / OS 3105-77) (Xenorhabdus luminescens (strain 2)). OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; OC Morganellaceae; Photorhabdus. OX NCBI_TaxID=553480 {ECO:0000313|EMBL:CAR67460.1}; RN [1] {ECO:0000313|EMBL:CAR67460.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=ATCC 43949 {ECO:0000313|EMBL:CAR67460.1}; RX PubMed=18838673; DOI=10.1073/pnas.0711114105; RA Waterfield N.R., Sanchez-Contreras M., Eleftherianos I., Dowling A., RA Wilkinson P., Parkhill J., Thomson N., Reynolds S.E., Bode H.B., RA Dorus S., Ffrench-Constant R.H.; RT "Rapid virulence annotation (RVA): identification of virulence factors RT using a bacterial genome library and multiple invertebrate hosts."; RL Proc. Natl. Acad. Sci. U.S.A. 105:15967-15972(2008). RN [2] {ECO:0000313|EMBL:CAR67460.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=ATCC 43949 {ECO:0000313|EMBL:CAR67460.1}; RA Thomson N.R.; RL Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|EMBL:CAQ83019.1, ECO:0000313|Proteomes:UP000002747} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 43949 / 3105-77 {ECO:0000313|Proteomes:UP000002747}, and RC ATCC43949 {ECO:0000313|EMBL:CAQ83019.1}; RX PubMed=19583835; DOI=10.1186/1471-2164-10-302; RA Wilkinson P., Waterfield N.R., Crossman L., Corton C., RA Sanchez-Contreras M., Vlisidou I., Barron A., Bignell A., Clark L., RA Ormond D., Mayho M., Bason N., Smith F., Simmonds M., Churcher C., RA Harris D., Thompson N.R., Quail M., Parkhill J., RA ffrench-Constant R.H.; RT "Comparative genomics of the emerging human pathogen Photorhabdus RT asymbiotica with the insect pathogen Photorhabdus luminescens."; RL BMC Genomics 10:302-302(2009). CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family. CC {ECO:0000256|RuleBase:RU003345}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; FM162591; CAQ83019.1; -; Genomic_DNA. DR EMBL; FM211056; CAR67460.1; -; Genomic_DNA. DR ProteinModelPortal; B6VMT0; -. DR STRING; 553480.PAU_00927; -. DR EnsemblBacteria; CAQ83019; CAQ83019; PAU_00927. DR KEGG; pay:PAU_00927; -. DR PATRIC; 20495535; VBIPhoAsy71438_1050. DR eggNOG; ENOG4105C26; Bacteria. DR eggNOG; COG1012; LUCA. DR HOGENOM; HOG000271509; -. DR KO; K00135; -. DR OMA; LGPLINN; -. DR OrthoDB; POG091H05FS; -. DR Proteomes; UP000002747; Chromosome. DR GO; GO:0009013; F:succinate-semialdehyde dehydrogenase [NAD(P)+] activity; IEA:InterPro. DR GO; GO:0009450; P:gamma-aminobutyric acid catabolic process; IEA:InterPro. DR Gene3D; 3.40.309.10; -; 1. DR Gene3D; 3.40.605.10; -; 1. DR InterPro; IPR016161; Ald_DH/histidinol_DH. DR InterPro; IPR016163; Ald_DH_C. DR InterPro; IPR016160; Ald_DH_CS_CYS. DR InterPro; IPR029510; Ald_DH_CS_GLU. DR InterPro; IPR016162; Ald_DH_N. DR InterPro; IPR015590; Aldehyde_DH_dom. DR InterPro; IPR010102; Succ_semiAld_DH. DR Pfam; PF00171; Aldedh; 1. DR SUPFAM; SSF53720; SSF53720; 1. DR TIGRFAMs; TIGR01780; SSADH; 1. DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1. DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1. PE 3: Inferred from homology; KW Complete proteome {ECO:0000313|Proteomes:UP000002747}; KW Oxidoreductase {ECO:0000256|RuleBase:RU003345}. FT DOMAIN 21 480 Aldedh. {ECO:0000259|Pfam:PF00171}. SQ SEQUENCE 491 AA; 52463 MW; DDDE70FF1060B94A CRC64; MTNNNVNIAL LRQQAYINGQ WIDADNKVTF NVANPANGEV IAQVSDLGAA ETERAIEAAQ QALPTWRAMT AKQRSQLLQR WFQLIMENQQ ALAELLSLEQ GKPPAEAMGE IAYGANFIEW FAEEGKRTYG ETIPSPLPGR RLITIKQPIG VVAAITPWNF PNAMITRKVG PALAAGCTVV LKPASETPLS ALALAALAEQ AGIPAGVLNV VTGINAKTIG GVLTRSPIIR KLSFTGSTRI GKLLMAQSAD TVKKLSLELG GNAPFIVFDD ADIDAAVQGA LTAKFRNSGQ TCVCANRILV QETIYDTFAT RLAQAVNTLH VGPASDVKSQ QGPLINQAAI DKVQEHISDA ISHGARILTG GKPHALGGLF FEPTVLADVN ESMLVSHEET FGPIAPLFKF RDEAEAIQLA NDTEFGLAAY FYSRDIGRIY RVAEALESGM VGINEGLISN EAAPFGGIKQ SGLGREGSRY GIEDYLEVKY LCFGGIEDAG A //