ID ERA_HELP2 Reviewed; 301 AA. AC B6JL99; DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot. DT 16-DEC-2008, sequence version 1. DT 15-DEC-2009, entry version 8. DE RecName: Full=GTP-binding protein era homolog; GN Name=era; OrderedLocusNames=HPP12_0523; OS Helicobacter pylori (strain P12). OC Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; OC Helicobacteraceae; Helicobacter. OX NCBI_TaxID=570508; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Fischer W., Windhager L., Karnholz A., Zeiller M., Zimmer R., Haas R.; RT "The complete genome sequence of Helicobacter pylori strain P12."; RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Binds both GDP and GTP, has an intrinsic GTPase activity CC and is essential for cell growth (By similarity). CC -!- SIMILARITY: Belongs to the era/mnmE GTP-binding protein family. CC Era subfamily. CC -!- SIMILARITY: Contains 1 KH type-2 domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP001217; ACJ07677.1; -; Genomic_DNA. DR RefSeq; YP_002301157.1; -. DR GeneID; 7010898; -. DR GenomeReviews; CP001217_GR; HPP12_0523. DR KEGG; hpp:HPP12_0523; -. DR HOGENOM; HBG561652; -. DR GO; GO:0005622; C:intracellular; IEA:InterPro. DR GO; GO:0005525; F:GTP binding; IEA:HAMAP. DR GO; GO:0003723; F:RNA binding; IEA:HAMAP. DR HAMAP; MF_00367; -; 1. DR InterPro; IPR005662; Era_GTP_bd. DR InterPro; IPR015946; KH-like_a/b. DR InterPro; IPR009019; KH_prok-type. DR InterPro; IPR004044; KH_type_2. DR InterPro; IPR002917; MMR_HSR1_GTP_bd. DR InterPro; IPR005225; Small_GTP_bd. DR Gene3D; G3DSA:3.30.300.20; KH_prok; 1. DR Pfam; PF07650; KH_2; 1. DR Pfam; PF01926; MMR_HSR1; 1. DR PROSITE; PS50823; KH_TYPE_2; 1. PE 3: Inferred from homology; KW Complete proteome; GTP-binding; Nucleotide-binding; RNA-binding. FT CHAIN 1 301 GTP-binding protein era homolog. FT /FTId=PRO_1000121331. FT DOMAIN 204 280 KH type-2. FT NP_BIND 12 19 GTP (Potential). FT NP_BIND 64 68 GTP (Potential). FT NP_BIND 122 125 GTP (Potential). SQ SEQUENCE 301 AA; 34422 MW; 92994DE2DA728BB5 CRC64; MKTKAGFVAL IGKPNAGKST LLNTLLNAHL ALVSHKANAT RKLMKCIVPF KDKEGYESQI IFLDTPGLHH QEKLLNQCML SQALKAMGDA ELCVFLASVH DDLKGYEEFL SLCQKPHILA LSKIDTATHK QVLQKLQEYQ QYDSQFLALV PLSAKKSQNL NALLECISKH LNPSAWLFEK DLMSDEKMRD IYKEIIRESL FDFLSDEIPY ESDVMIDKFI EEERIDKVYA RIIVEKESQK KIVIGKNGVN IKRIGTSARL KMQEVGEKKV FLNLQVIAQK SWSKEEKSLQ KLGYTHQRNR D //