ID KDUI_ECO5E Reviewed; 278 AA. AC B5Z4G1; DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot. DT 25-NOV-2008, sequence version 1. DT 19-JAN-2010, entry version 14. DE RecName: Full=4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; DE EC=5.3.1.17; DE AltName: Full=5-keto-4-deoxyuronate isomerase; DE AltName: Full=DKI isomerase; GN Name=kduI; OrderedLocusNames=ECH74115_4112; OS Escherichia coli O157:H7 (strain EC4115 / EHEC). OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Escherichia. OX NCBI_TaxID=444450; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Eppinger M., Sebastian Y., Ravel J.; RT "Complete genome sequence of Escherichia coli O157:H7 str. EC4115."; RL Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: 4-deoxy-L-threo-5-hexosulose uronate = 3- CC deoxy-D-glycero-2,5-hexodiulosonate. CC -!- PATHWAY: Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy- CC D-gluconate from pectin: step 4/5. CC -!- SUBUNIT: Homohexamer (By similarity). CC -!- SIMILARITY: Belongs to the kduI family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP001164; ACI38163.1; -; Genomic_DNA. DR RefSeq; YP_002272307.1; -. DR SMR; B5Z4G1; 1-277. DR GeneID; 6971923; -. DR GenomeReviews; CP001164_GR; ECH74115_4112. DR KEGG; ecf:ECH74115_4112; -. DR HOGENOM; HBG301328; -. DR OMA; QAVISPP; -. DR GO; GO:0008697; F:4-deoxy-L-threo-5-hexosulose-uronate ketol-...; IEA:HAMAP. DR GO; GO:0045490; P:pectin catabolic process; IEA:InterPro. DR HAMAP; MF_00687; KduI; 1; -. DR InterPro; IPR011051; Cupin_RmlC_type. DR InterPro; IPR007045; KduI. DR Pfam; PF04962; KduI; 1. DR PIRSF; PIRSF006625; KduI; 1. PE 3: Inferred from homology; KW Complete proteome; Isomerase. FT CHAIN 1 278 4-deoxy-L-threo-5-hexosulose-uronate FT ketol-isomerase. FT /FTId=PRO_1000131879. SQ SEQUENCE 278 AA; 31090 MW; B8E4098A31BEB6A2 CRC64; MDVRQSIHSA HAKTLETQGL RNEFLVEKVF VADEYTMVYS HIDRIIIGGI MPVTKTVSVG GEVGKQLGVS YFLERRELGV INIGGAGTIT VDGQCYEIGH RDALYVGKGA KEVVFASIDT GTPAKFYYNC APAHTTYPTK KVTPDEVSPV TLGDNLTSNR RTINKYFVPD VLETCQLSMG LTELAPGNLW NTMPCHTHER RMEVYFYFNM DDDACVFHMM GQPQETRHIV MHNEQAVISP SWSIHSGVGT KAYTFIWGMV GENQVFDDMD HVAVKDLR //