ID BAMA_KLEP3 Reviewed; 809 AA. AC B5Y1J4; DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot. DT 25-NOV-2008, sequence version 1. DT 14-DEC-2022, entry version 65. DE RecName: Full=Outer membrane protein assembly factor BamA {ECO:0000255|HAMAP-Rule:MF_01430}; DE Flags: Precursor; GN Name=bamA {ECO:0000255|HAMAP-Rule:MF_01430}; Synonyms=yaeT; GN OrderedLocusNames=KPK_4543; OS Klebsiella pneumoniae (strain 342). OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella. OX NCBI_TaxID=507522; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=342; RX PubMed=18654632; DOI=10.1371/journal.pgen.1000141; RA Fouts D.E., Tyler H.L., DeBoy R.T., Daugherty S., Ren Q., Badger J.H., RA Durkin A.S., Huot H., Shrivastava S., Kothari S., Dodson R.J., Mohamoud Y., RA Khouri H., Roesch L.F.W., Krogfelt K.A., Struve C., Triplett E.W., RA Methe B.A.; RT "Complete genome sequence of the N2-fixing broad host range endophyte RT Klebsiella pneumoniae 342 and virulence predictions verified in mice."; RL PLoS Genet. 4:E1000141-E1000141(2008). CC -!- FUNCTION: Part of the outer membrane protein assembly complex, which is CC involved in assembly and insertion of beta-barrel proteins into the CC outer membrane. Constitutes, with BamD, the core component of the CC assembly machinery. {ECO:0000255|HAMAP-Rule:MF_01430}. CC -!- SUBUNIT: Part of the Bam complex, which is composed of the outer CC membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE. CC {ECO:0000255|HAMAP-Rule:MF_01430}. CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP- CC Rule:MF_01430}. CC -!- SIMILARITY: Belongs to the BamA family. {ECO:0000255|HAMAP- CC Rule:MF_01430}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000964; ACI09166.1; -; Genomic_DNA. DR AlphaFoldDB; B5Y1J4; -. DR SMR; B5Y1J4; -. DR EnsemblBacteria; ACI09166; ACI09166; KPK_4543. DR KEGG; kpe:KPK_4543; -. DR HOGENOM; CLU_007664_1_0_6; -. DR OMA; IFMPAFG; -. DR OrthoDB; 258122at2; -. DR Proteomes; UP000001734; Chromosome. DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell. DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule. DR GO; GO:0051205; P:protein insertion into membrane; IEA:UniProtKB-UniRule. DR HAMAP; MF_01430; OM_assembly_BamA; 1. DR InterPro; IPR000184; Bac_surfAg_D15. DR InterPro; IPR010827; BamA/TamA_POTRA. DR InterPro; IPR039910; D15-like. DR InterPro; IPR023707; OM_assembly_BamA. DR InterPro; IPR034746; POTRA. DR PANTHER; PTHR12815:SF23; OUTER MEMBRANE PROTEIN ASSEMBLY FACTOR BAMA; 1. DR PANTHER; PTHR12815; SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER; 1. DR Pfam; PF01103; Omp85; 1. DR Pfam; PF07244; POTRA; 4. DR PIRSF; PIRSF006076; OM_assembly_OMP85; 1. DR TIGRFAMs; TIGR03303; OM_YaeT; 1. DR PROSITE; PS51779; POTRA; 5. PE 3: Inferred from homology; KW Cell outer membrane; Membrane; Repeat; Signal; Transmembrane; KW Transmembrane beta strand. FT SIGNAL 1..20 FT /evidence="ECO:0000255|HAMAP-Rule:MF_01430" FT CHAIN 21..809 FT /note="Outer membrane protein assembly factor BamA" FT /id="PRO_1000145780" FT DOMAIN 24..91 FT /note="POTRA 1" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115" FT DOMAIN 92..172 FT /note="POTRA 2" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115" FT DOMAIN 175..263 FT /note="POTRA 3" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115" FT DOMAIN 266..344 FT /note="POTRA 4" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115" FT DOMAIN 347..421 FT /note="POTRA 5" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115" SQ SEQUENCE 809 AA; 89908 MW; 86A0EF05CAE08010 CRC64; MAMKKLLIAS LLFSSATVYG AEGFVVKDIH FEGLQRVAVG AALLSMPVRP GDTVTDDDIS NTIRALFATG NFEDVRVLRD GDTLLVQVKE RPTIASITFS GNKSVKDDML KQNLEASGVR VGESLDRTTI ADIEKGLEDF YYSVGKYSAS VKAVVTPLPR NRVDLKLVFQ EGVSAKIQQI NIVGNHAFST DELISHFQLR DEVPWWNVVG DRKYQKQKLA GDLETLRSYY LDRGYARFNI DSTQVSLTPD KKGIYITVNI TEGDQYKISG VQVTGDLAGH SAEIEALTKV EPGELYNGAK VTKMENDIKK LLGRYGYAYP RVQSQPEIND SDKTVKLHVN VDAGNRYYVR KIRFEGNDTS KDAVLRREMR QMEGAWLGSD LVDQGKDRLN RLGFFETVDT DTQRVPGSPD QVDVVYKVKE RNTGSFNFGI GYGTESGVSF QAGVQQDNWL GTGYAVGING TKNDYQTYTE LSVTNPYFTV DGVSLGGRIF YNDFDANDAD LSDYTNKSYG TDVTLGFPVN EYNTLRAGVG YVHNSLSNMQ PQVAMWRYLN SMGQYPDNTN DRNSFSANDF TFNYGWTYNK LDRGFFPTEG SRVNLNGKVT IPGSDNEYYK ATLDTATYVP IDNDHQWVVL GRTRFGYGDG IGGKEMPFYE NFYAGGSSTV RGFQSNTIGP KAVYFPSSSR HDGDSGYTND CKSTESAPCK SDDAVGGNAM AVASLELITP TPFISDKYAN SVRTSVFWDM GTVWDTHWDS NAYGGYPDYS DPSNIRMSAG IAVQWMSPLG PLVFSYAQPF KKYDGDKAEQ FQFNIGKTW //