ID B5LUF1_9HIV1 Unreviewed; 240 AA. AC B5LUF1; DT 14-OCT-2008, integrated into UniProtKB/TrEMBL. DT 14-OCT-2008, sequence version 1. DT 27-MAR-2024, entry version 33. DE SubName: Full=Pol protein {ECO:0000313|EMBL:ACH42939.1}; DE Flags: Fragment; GN Name=pol {ECO:0000313|EMBL:ACH42939.1}; OS Human immunodeficiency virus 1. OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; OC Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus. OX NCBI_TaxID=11676 {ECO:0000313|EMBL:ACH42939.1}; OH NCBI_TaxID=9606; Homo sapiens (Human). RN [1] {ECO:0000313|EMBL:ACH42939.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=TM2607p {ECO:0000313|EMBL:ACH42939.1}; RA Smolen J.J.; RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:ACH42939.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=TM2607p {ECO:0000313|EMBL:ACH42939.1}; RX PubMed=20624076; DOI=10.1089/aid.2009.0172; RA Smolen J., Kruszynski P., Bratosiewicz-Wasik J., Witor A., Wasik T.J.; RT "HIV type 1 genetic diversity in Silesia, Poland: a retrospective RT analysis."; RL AIDS Res. Hum. Retroviruses 26:767-776(2010). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EU910752; ACH42939.1; -; Genomic_DNA. DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW. DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW. DR Gene3D; 3.30.70.270; -; 1. DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1. DR InterPro; IPR043502; DNA/RNA_pol_sf. DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase. DR InterPro; IPR000477; RT_dom. DR PANTHER; PTHR41694; ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN; 1. DR PANTHER; PTHR41694:SF3; RNA-DIRECTED DNA POLYMERASE-RELATED; 1. DR Pfam; PF00078; RVT_1; 1. DR SUPFAM; SSF56672; DNA/RNA polymerases; 1. DR PROSITE; PS50878; RT_POL; 1. PE 4: Predicted; KW Endonuclease {ECO:0000256|ARBA:ARBA00022759}; KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}; KW Nuclease {ECO:0000256|ARBA:ARBA00022722}; KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695}; KW RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022918}; KW Transferase {ECO:0000256|ARBA:ARBA00022679}; KW Viral release from host cell {ECO:0000256|ARBA:ARBA00023113}; KW Virion maturation {ECO:0000256|ARBA:ARBA00023113}. FT DOMAIN 31..221 FT /note="Reverse transcriptase" FT /evidence="ECO:0000259|PROSITE:PS50878" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:ACH42939.1" FT NON_TER 240 FT /evidence="ECO:0000313|EMBL:ACH42939.1" SQ SEQUENCE 240 AA; 27988 MW; BE7BA9F1821E7D79 CRC64; PGMDGPKVKQ WPLTEEKIKA LIEICTEMEK EGKISKIGPE NPYNTPVFAI KKKDGTKWRK LVDFRELNKR TQDFWEVQLG IPHPAGLKKK KSVTVLDVGD AYFSVPLDQD FRKYTAFTIP STNNETPGIR YQYNVLPQGW KGSPAIFQSS MIKILEPFRK QNPDIVIYQY MDDLYVGSDL EIGQHRTKIE ELRQHLLKWG FTTPDKKHQK EPPFLWMGYE LHPDKWTVQP IVLPEKDSWT //