ID B5LBD0_9INFA Unreviewed; 443 AA. AC B5LBD0; DT 14-OCT-2008, integrated into UniProtKB/TrEMBL. DT 14-OCT-2008, sequence version 1. DT 18-MAY-2010, entry version 13. DE SubName: Full=Neuraminidase; DE Flags: Fragment; GN Name=NA; OS Influenza A virus (A/turkey/England/N28/73(H5N2)). OC Viruses; ssRNA negative-strand viruses; Orthomyxoviridae; OC Influenzavirus A. OX NCBI_TaxID=236240; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=A/turkey/England/N28/73; RX PubMed=18753228; DOI=10.1099/vir.0.2008/001875-0; RA Zhao Z.M., Shortridge K.F., Garcia M., Guan Y., Wan X.F.; RT "Genotypic diversity of H5N1 highly pathogenic avian influenza RT viruses."; RL J. Gen. Virol. 89:2182-2193(2008). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=A/turkey/England/N28/73; RA Zhao Z., Garcia M., Guan Y., Shortridge K.F., Wan X.-F.; RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, CC alpha-(2->8)- glycosidic linkages of terminal sialic acid residues CC in oligosaccharides, glycoproteins, glycolipids, colominic acid CC and synthetic substrates.. CC -!- SUBUNIT: Homotetramer. (By similarity). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EU636686; ACF40959.1; -; Viral_cRNA. DR GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-KW. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. DR GO; GO:0019012; C:virion; IEA:UniProtKB-KW. DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro. DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. DR InterPro; IPR001860; Glyco_hydro_34. DR InterPro; IPR011040; Neuraminidase. DR Pfam; PF00064; Neur; 1. DR SUPFAM; SSF50939; Sialidase; 1. PE 3: Inferred from homology; KW Glycosidase; Host cell membrane; Host membrane; Hydrolase; Membrane; KW Transmembrane; Virion. FT NON_TER 1 1 FT NON_TER 443 443 SQ SEQUENCE 443 AA; 49079 MW; C196569260DDD8A4 CRC64; FLMQIAILAT TVTLHFKQHE CNPPAINQVT PCEPIIVERN ITEIVYLNST SIEREICPEA VEYRNWSKPQ CQITGFAPFS KDNSIRLSAG GDIWVTREPY VSCDPGKCYQ FALGQGTTLD NKHSNGTIHD RIPHRTLLMN ELGVPFHLGT KQVCIAWSSS SCHDGRAWLH ICVTGDDRNA TASFIYDGRL VDSIGSWSQN ILRTQESECV CINGTCTVVM TDGSASGRAD TRILFIKEGK IVHISPLSGS AQHIEECSCY PRYPDVRCIC RDNWKGSNRP VIDINMADYS IDSSYVCSGL VGDTPRNDDS SSSSNCRDPN NERGNPGVKG WAFDNGDDVW MGRTISKDSR SGYETFKVIG GWSTPNSKSQ VNRQVIVDNN NRSGYSGIFS VEGKSCINRC FYVELIRGRP QETRVWWTSN SIVVFCGTSG TYGTGSWPDG ANI //