ID B5A931_HUMAN Unreviewed; 755 AA. AC B5A931; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 24-JUN-2015, entry version 40. DE SubName: Full=Soluble MET variant 3 {ECO:0000313|EMBL:ACF47605.1}; GN Name=MET {ECO:0000313|EMBL:ACF47605.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:ACF47605.1}; RN [1] {ECO:0000313|EMBL:ACF47605.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=18593464; DOI=10.1186/ar2447; RA Jin P., Zhang J., Sumariwalla P.F., Ni I., Jorgensen B., Crawford D., RA Phillips S., Feldmann M., Shepard H.M., Paleolog E.M.; RT "Novel splice variants derived from the receptor tyrosine kinase RT superfamily are potential therapeutics for rheumatoid arthritis."; RL Arthritis Res. Ther. 10:R73-R73(2008). CC -!- SIMILARITY: Contains Sema domain. {ECO:0000256|SAAS:SAAS00115753}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EU826569; ACF47605.1; -; mRNA. DR UniGene; Hs.132966; -. DR STRING; 9606.ENSP00000317272; -. DR HOVERGEN; HBG104341; -. DR ChiTaRS; MET; human. DR NextBio; 35477755; -. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR Gene3D; 2.130.10.10; -; 1. DR Gene3D; 2.60.40.10; -; 2. DR InterPro; IPR013783; Ig-like_fold. DR InterPro; IPR014756; Ig_E-set. DR InterPro; IPR002909; IPT. DR InterPro; IPR016201; Plexin-like_fold. DR InterPro; IPR002165; Plexin_repeat. DR InterPro; IPR001627; Semap_dom. DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom. DR Pfam; PF01437; PSI; 1. DR Pfam; PF01403; Sema; 1. DR Pfam; PF01833; TIG; 2. DR SMART; SM00429; IPT; 2. DR SMART; SM00423; PSI; 1. DR SMART; SM00630; Sema; 1. DR SUPFAM; SSF101912; SSF101912; 1. DR SUPFAM; SSF103575; SSF103575; 1. DR SUPFAM; SSF81296; SSF81296; 2. DR PROSITE; PS51004; SEMA; 1. PE 2: Evidence at transcript level; KW Disulfide bond {ECO:0000256|SAAS:SAAS00037641}; KW Membrane {ECO:0000256|SAAS:SAAS00106065}; KW Repeat {ECO:0000256|SAAS:SAAS00037635}; KW Transmembrane {ECO:0000256|SAAS:SAAS00037688}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS00037627}. SQ SEQUENCE 755 AA; 84591 MW; 461BD63772FF9896 CRC64; MKAPAVLAPG ILVLLFTLVQ RSNGECKEAL AKSEMNVNMK YQLPNFTAET PIQNVILHEH HIFLGATNYI YVLNEEDLQK VAEYKTGPVL EHPDCFPCQD CSSKANLSGG VWKDNINMAL VVDTYYDDQL ISCGSVNRGT CQRHVFPHNH TADIQSEVHC IFSPQIEEPS QCPDCVVSAL GAKVLSSVKD RFINFFVGNT INSSYFPDHP LHSISVRRLK ETKDGFMFLT DQSYIDVLPE FRDSYPIKYV HAFESNNFIY FLTVQRETLD AQTFHTRIIR FCSINSGLHS YMEMPLECIL TEKRKKRSTK KEVFNILQAA YVSKPGAQLA RQIGASLNDD ILFGVFAQSK PDSAEPMDRS AMCAFPIKYV NDFFNKIVNK NDVRCLQHFY GPNHEHCFNG TLLRNSSGCE ARRDEYRTEF TTALQRVDLF MGQFSEVLLT SISTFIKGDL TIANLGTSEG RFMQVVVSRS GPSTPRVNFL LDSHPVSPEV IVEHTLNQNG YTLVITGKKI TKIPLNGLGC RHFQSCSQCL SAPPFVQCGW CYDKCVRSEE CLSGTWTQQI CLPAIYKVFP NSAPLEGGTR LTICGWDFGF RRNNKFDLKK TRVLLGNESC TLTLSESTMN TSKCTVGPAM NKHFNMSIII SNGHGTTQYS TFSYVDPVIT SISPKYGPMA GGTLLTLTGN YLNSGNSRHI SIGGKTCTLK SVSNSILECY TPAQTISTEF AVKLKIDLAN RETSIFSYRE DPIVYVIHPT KSFIR //