ID B5A219_HUMAN Unreviewed; 29 AA. AC B5A219; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 24-JAN-2024, entry version 58. DE RecName: Full=histone acetyltransferase {ECO:0000256|ARBA:ARBA00013184}; DE EC=2.3.1.48 {ECO:0000256|ARBA:ARBA00013184}; DE Flags: Fragment; GN Name=CREBBP {ECO:0000313|EMBL:ACF57242.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:ACF57242.1}; RN [1] {ECO:0000313|EMBL:ACF57242.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=20689175; DOI=10.1007/s12038-010-0023-5; RA Sharma N., Mali A.M., Bapat S.A.; RT "Spectrum of CREBBP mutations in Indian patients with Rubinstein-Taybi RT syndrome."; RL J. Biosci. 35:187-202(2010). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EU790727; ACF57242.1; -; Genomic_DNA. DR AlphaFoldDB; B5A219; -. DR PeptideAtlas; B5A219; -. DR ChiTaRS; CREBBP; human. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW. DR GO; GO:0004402; F:histone acetyltransferase activity; IEA:InterPro. DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro. DR InterPro; IPR031162; CBP_P300_HAT. DR InterPro; IPR013178; Histone_AcTrfase_Rtt109/CBP. DR PANTHER; PTHR13808; CBP/P300-RELATED; 1. DR PANTHER; PTHR13808:SF34; CREB-BINDING PROTEIN; 1. DR Pfam; PF08214; HAT_KAT11; 1. DR PROSITE; PS51727; CBP_P300_HAT; 1. PE 4: Predicted; KW Nucleus {ECO:0000256|ARBA:ARBA00023242}; KW Transcription {ECO:0000256|ARBA:ARBA00023163}; KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}; KW Transferase {ECO:0000256|ARBA:ARBA00022679}. FT DOMAIN 1..29 FT /note="CBP/p300-type HAT" FT /evidence="ECO:0000259|PROSITE:PS51727" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:ACF57242.1" FT NON_TER 29 FT /evidence="ECO:0000313|EMBL:ACF57242.1" SQ SEQUENCE 29 AA; 3324 MW; DEF95D138BFB4700 CRC64; YVTGHIWACP PSEGDDYIFH CHPPDQKIP //