ID B4X635_9CHIR Unreviewed; 137 AA. AC B4X635; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 25-MAY-2022, entry version 32. DE RecName: Full=Cytochrome b {ECO:0000256|ARBA:ARBA00013531}; DE AltName: Full=Complex III subunit 3 {ECO:0000256|ARBA:ARBA00031681}; DE AltName: Full=Complex III subunit III {ECO:0000256|ARBA:ARBA00032600}; DE AltName: Full=Cytochrome b-c1 complex subunit 3 {ECO:0000256|ARBA:ARBA00029812}; DE AltName: Full=Ubiquinol-cytochrome-c reductase complex cytochrome b subunit {ECO:0000256|ARBA:ARBA00032818}; DE Flags: Fragment; GN Name=cytb {ECO:0000313|EMBL:ABQ12908.1}; OS Rhinolophus sedulus (lesser woolly horseshoe bat). OG Mitochondrion {ECO:0000313|EMBL:ABQ12908.1}. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Rhinolophidae; OC Rhinolophinae; Rhinolophus. OX NCBI_TaxID=59480 {ECO:0000313|EMBL:ABQ12908.1}; RN [1] {ECO:0000313|EMBL:ABQ12908.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=KNP031 {ECO:0000313|EMBL:ABQ12908.1}, and MWC003 RC {ECO:0000313|EMBL:ABQ12909.1}; RA Sazali S.N., Abdullah M.T.; RT "Phylogenetic Relationships of Rhinolophus, Hipposideros, Megaderma and RT Nycteris Using Partial Cytochrome b Gene Sequences."; RL Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Component of the ubiquinol-cytochrome c reductase complex CC (complex III or cytochrome b-c1 complex) that is part of the CC mitochondrial respiratory chain. The b-c1 complex mediates electron CC transfer from ubiquinol to cytochrome c. Contributes to the generation CC of a proton gradient across the mitochondrial membrane that is then CC used for ATP synthesis. {ECO:0000256|ARBA:ARBA00002566}. CC -!- COFACTOR: CC Name=heme; Xref=ChEBI:CHEBI:30413; CC Evidence={ECO:0000256|ARBA:ARBA00001971}; CC -!- SUBUNIT: The cytochrome bc1 complex contains 11 subunits: 3 respiratory CC subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and CC UQCRC2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, CC UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of CC UQCRFS1). This cytochrome bc1 complex then forms a dimer. CC {ECO:0000256|ARBA:ARBA00011088}. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion CC inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane CC protein {ECO:0000256|ARBA:ARBA00004448}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EF108173; ABQ12908.1; -; Genomic_DNA. DR EMBL; EF108174; ABQ12909.1; -; Genomic_DNA. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. DR GO; GO:0070469; C:respirasome; IEA:UniProtKB-KW. DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro. DR GO; GO:0022904; P:respiratory electron transport chain; IEA:InterPro. DR CDD; cd00284; Cytochrome_b_N; 1. DR Gene3D; 1.20.810.10; -; 1. DR InterPro; IPR005797; Cyt_b/b6_N. DR InterPro; IPR027387; Cytb/b6-like_sf. DR InterPro; IPR016174; Di-haem_cyt_TM. DR Pfam; PF00033; Cytochrome_B; 1. DR SUPFAM; SSF81342; SSF81342; 1. DR PROSITE; PS51002; CYTB_NTER; 1. PE 4: Predicted; KW Electron transport {ECO:0000256|ARBA:ARBA00022982}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128, ECO:0000313|EMBL:ABQ12908.1}; KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792}; KW Respiratory chain {ECO:0000256|ARBA:ARBA00022660}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}; KW Ubiquinone {ECO:0000256|ARBA:ARBA00023075}. FT TRANSMEM 28..50 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 79..101 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 113..131 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 1..137 FT /note="CYTB_NTER" FT /evidence="ECO:0000259|PROSITE:PS51002" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:ABQ12908.1" FT NON_TER 137 FT /evidence="ECO:0000313|EMBL:ABQ12908.1" SQ SEQUENCE 137 AA; 15482 MW; F258E78B6D473E1E CRC64; NIRKSHPLFK IINDSFVDLP APSSISSWWN FGSLLGVCLA VQILTGLFLA MHYTSDTTTA FYSVTHICRD VNYGWILRYL HANGASMFFI CLFLHVGRGI YYGSYTFSET WNIGILLLFA VMATAFMGYV LPWGQMS //