ID NUDC_SALHS Reviewed; 257 AA. AC B4TCT5; DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot. DT 23-SEP-2008, sequence version 1. DT 22-SEP-2009, entry version 10. DE RecName: Full=NADH pyrophosphatase; DE EC=3.6.1.22; GN Name=nudC; OrderedLocusNames=SeHA_C4497; OS Salmonella heidelberg (strain SL476). OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Salmonella; OC Salmonella enterica subsp. enterica serovar Heidelberg. OX NCBI_TaxID=454169; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Ravel J., Fricke W.F., White D., McDermott P., Mammel M., Rosovitz M., RA Leclerc J., Cebula T., Sebastian Y.; RT "Complete genome of Salmonella heidelberg strain SL476."; RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: NAD(+) + H(2)O = AMP + NMN. CC -!- COFACTOR: Divalent ions. Manganese or magnesium (By similarity). CC -!- SUBUNIT: Homodimer (By similarity). CC -!- SIMILARITY: Belongs to the Nudix hydrolase family. NudC subfamily. CC -!- SIMILARITY: Contains 1 nudix hydrolase domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP001120; ACF66801.1; -; Genomic_DNA. DR RefSeq; YP_002048151.1; -. DR GeneID; 6491073; -. DR GenomeReviews; CP001120_GR; SeHA_C4497. DR KEGG; seh:SeHA_C4497; -. DR OMA; B4TCT5; SPCIIVA. DR GO; GO:0000287; F:magnesium ion binding; IEA:HAMAP. DR GO; GO:0030145; F:manganese ion binding; IEA:HAMAP. DR GO; GO:0000210; F:NAD+ diphosphatase activity; IEA:HAMAP. DR HAMAP; MF_00297; -; 1. DR InterPro; IPR015375; NADH_PPase-like_N. DR InterPro; IPR020084; NUDIX_hydrolase_CS. DR InterPro; IPR000086; NUDIX_hydrolase_dom. DR InterPro; IPR015376; Znr_NADH_PPase. DR Gene3D; G3DSA:3.90.79.10; NUDIX_hydrolase; 1. DR Pfam; PF00293; NUDIX; 1. DR Pfam; PF09296; NUDIX-like; 1. DR Pfam; PF09297; zf-NADH-PPase; 1. DR PROSITE; PS51462; NUDIX; 1. DR PROSITE; PS00893; NUDIX_BOX; 1. PE 3: Inferred from homology; KW Complete proteome; Hydrolase; Magnesium; Manganese; NAD. FT CHAIN 1 257 NADH pyrophosphatase. FT /FTId=PRO_1000115250. FT DOMAIN 125 248 Nudix hydrolase. FT MOTIF 159 180 Nudix box. SQ SEQUENCE 257 AA; 29635 MW; D8F0B689D0F4555C CRC64; MDRIIEKLES GWWIVSHEQK LWLPYGELPH GLAANFDLVG QRALRIGEWQ GEPVWLVLQH RRHDMGSVRQ VIDQDAGLFQ LAGRGVQLAE FYRSHKFCGY CGHPMHPSKT EWAMLCSHCR ERYYPQIAPC IIVAIRREDS ILLARHVRHR NGVHTVLAGF VEVGETLEQA VAREVMEESG IKVKNLRYVT SQPWPFPQSL MTAFMAEYDS GEIVIDPKEL LEANWYRYDD LPLLPPPGTV ARRLIEDTVA MCRAEYD //