ID B4DWI9_HUMAN Unreviewed; 347 AA. AC B4DWI9; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 25-OCT-2017, entry version 42. DE SubName: Full=cDNA FLJ50898, highly similar to DNA-(apurinic or apyrimidinic site) lyase 2(EC 4.2.99.18) {ECO:0000313|EMBL:BAG63051.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG63051.1}; RN [1] {ECO:0000313|EMBL:BAG63051.1} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Breast {ECO:0000313|EMBL:BAG63051.1}; RA Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., RA Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., RA Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., RA Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.; RT "NEDO human cDNA sequencing project focused on splicing variants."; RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK301555; BAG63051.1; -; mRNA. DR RefSeq; NP_001258677.1; NM_001271748.1. DR UniGene; Hs.659558; -. DR PaxDb; B4DWI9; -. DR PeptideAtlas; B4DWI9; -. DR PRIDE; B4DWI9; -. DR GeneID; 27301; -. DR CTD; 27301; -. DR eggNOG; KOG1294; Eukaryota. DR eggNOG; COG0708; LUCA. DR HOVERGEN; HBG054715; -. DR GenomeRNAi; 27301; -. DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW. DR GO; GO:0004518; F:nuclease activity; IEA:InterPro. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR GO; GO:0006281; P:DNA repair; IEA:InterPro. DR Gene3D; 3.60.10.10; -; 1. DR InterPro; IPR004808; AP_endonuc_1. DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf. DR InterPro; IPR005135; Endo/exonuclease/phosphatase. DR InterPro; IPR010666; Znf_GRF. DR PANTHER; PTHR22748; PTHR22748; 1. DR Pfam; PF03372; Exo_endo_phos; 1. DR Pfam; PF06839; zf-GRF; 1. DR SUPFAM; SSF56219; SSF56219; 1. DR PROSITE; PS51435; AP_NUCLEASE_F1_4; 1. PE 2: Evidence at transcript level; KW Lyase {ECO:0000313|EMBL:BAG63051.1}. FT DOMAIN 2 133 Endo/exonuclease/phosphatase. FT {ECO:0000259|Pfam:PF03372}. FT DOMAIN 296 344 zf-GRF. {ECO:0000259|Pfam:PF06839}. SQ SEQUENCE 347 AA; 38578 MW; C79E7A5774C5E84D CRC64; MRFYRLLQIR TEALLAAGSH VIILGDLNTA HRPIDHWDAV NLECFEEDPG RKWMDSLLSN LGCQSASHVG PFIDSYRCFQ PKQEGAFTCW SAVTGARHLN YGSRLDYVLG DRTLVIDTFQ ASFLLPEVMG SDHCPVGAVL SVSSVPAKQC PPLCTRFLPE FAGTQLKILR FLVPLEQSPV LEQSTLQHNN QTRVQTCQNK AQVRSTRPQP SQVGSSRGQK NLKSYFQPSP SCPQASPDIE LPSLPLMSAL MTPKTPEEKA VAKVVKGQAK TSEAKDEKEL RTSFWKSVLA GPLRTPLCGG HREPCVMRTV KKPGPNLGRR FYMCARPRGP PTDPSSRCNF FLWSRPS //