ID B4DQM5_HUMAN Unreviewed; 186 AA. AC B4DQM5; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 29-MAY-2024, entry version 33. DE SubName: Full=cDNA FLJ51277, highly similar to Ganglioside GM2 activator {ECO:0000313|EMBL:BAG60987.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG60987.1}; RN [1] {ECO:0000313|EMBL:BAG60987.1} RP NUCLEOTIDE SEQUENCE. RA Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., RA Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., RA Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T., RA Sugano S., Nomura N., Isogai T.; RT "NEDO human cDNA sequencing project focused on splicing variants."; RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK298867; BAG60987.1; -; mRNA. DR AlphaFoldDB; B4DQM5; -. DR SMR; B4DQM5; -. DR PeptideAtlas; B4DQM5; -. DR GO; GO:0009898; C:cytoplasmic side of plasma membrane; IEA:TreeGrafter. DR GO; GO:0008047; F:enzyme activator activity; IEA:InterPro. DR GO; GO:0005319; F:lipid transporter activity; IEA:TreeGrafter. DR GO; GO:0006689; P:ganglioside catabolic process; IEA:InterPro. DR Gene3D; 2.70.220.10; Ganglioside GM2 activator; 1. DR InterPro; IPR028996; GM2-AP. DR InterPro; IPR036846; GM2-AP_sf. DR InterPro; IPR003172; ML_dom. DR PANTHER; PTHR17357:SF0; GANGLIOSIDE GM2 ACTIVATOR; 1. DR PANTHER; PTHR17357; GM2 GANGLIOSIDE ACTIVATOR PROTEIN; 1. DR Pfam; PF02221; E1_DerP2_DerF2; 1. DR SUPFAM; SSF63707; Ganglioside M2 (gm2) activator; 1. PE 2: Evidence at transcript level; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1..23 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 24..186 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5002803506" FT DOMAIN 33..141 FT /note="MD-2-related lipid-recognition" FT /evidence="ECO:0000259|Pfam:PF02221" SQ SEQUENCE 186 AA; 20086 MW; BE6DD3DCF5D79B0B CRC64; MQSLMQAPLL IALGLLLAAP AQAHLKKPSQ LSSFSWDNCD EGKDPAVIRS LTLEPDPIVV PGNVTLSVVG STSVPLSSPL KVDLVLEKEV AGLWIKIPCT DYIGSCTFEH FCDVLDMLIP TGEPCPEPLR TYGLPCHCPF SSVLCLPRPN SHSLPPFNPL STVSPLPSLK IILYHLHFRL GQAALT //