ID B4DFA5_HUMAN Unreviewed; 221 AA. AC B4DFA5; F5GXG7; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 31-JUL-2019, entry version 77. DE SubName: Full=Protein LTO1 homolog {ECO:0000313|Ensembl:ENSP00000446428}; DE SubName: Full=cDNA FLJ58145, highly similar to Oral cancer overexpressed protein 1 {ECO:0000313|EMBL:BAG57366.1}; GN Name=LTO1 {ECO:0000313|Ensembl:ENSP00000446428}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG57366.1}; RN [1] {ECO:0000313|Ensembl:ENSP00000446428, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=16554811; DOI=10.1038/nature04632; RA Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., RA Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T., RA Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G., RA Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C., RA Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., RA Hattori M., Rogers J., Lander E.S., Sakaki Y.; RT "Human chromosome 11 DNA sequence and analysis including novel gene RT identification."; RL Nature 440:497-500(2006). RN [2] {ECO:0000313|EMBL:BAG57366.1} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Cerebellum {ECO:0000313|EMBL:BAG57366.1}; RA Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., RA Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., RA Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., RA Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.; RT "NEDO human cDNA sequencing project focused on splicing variants."; RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000213|PubMed:21406692} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21406692; DOI=10.1126/scisignal.2001570; RA Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., RA Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., RA Blagoev B.; RT "System-wide temporal characterization of the proteome and RT phosphoproteome of human embryonic stem cell differentiation."; RL Sci. Signal. 4:RS3-RS3(2011). RN [4] {ECO:0000313|Ensembl:ENSP00000446428} RP IDENTIFICATION. RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. RN [5] {ECO:0000213|PubMed:22814378} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=22814378; DOI=10.1073/pnas.1210303109; RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., RA Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., RA Aldabe R.; RT "N-terminal acetylome analyses and functional insights of the N- RT terminal acetyltransferase NatB."; RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AP001888; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AK294004; BAG57366.1; -; mRNA. DR jPOST; B4DFA5; -. DR MaxQB; B4DFA5; -. DR PRIDE; B4DFA5; -. DR ProteomicsDB; 24420; -. DR ProteomicsDB; 4018; -. DR Ensembl; ENST00000538554; ENSP00000446428; ENSG00000149716. DR UCSC; uc010rqh.2; human. DR HGNC; HGNC:17589; LTO1. DR OpenTargets; ENSG00000149716; -. DR eggNOG; KOG4595; Eukaryota. DR eggNOG; ENOG410XX62; LUCA. DR GeneTree; ENSGT00390000009426; -. DR HOGENOM; HOG000069904; -. DR ChiTaRS; ORAOV1; human. DR Proteomes; UP000005640; Chromosome 11. DR Bgee; ENSG00000149716; Expressed in 146 organ(s), highest expression level in vagina. DR ExpressionAtlas; B4DFA5; baseline and differential. DR InterPro; IPR019191; Essential_protein_Yae1_N. DR Pfam; PF09811; Yae1_N; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000005640}; KW Proteomics identification {ECO:0000213|MaxQB:B4DFA5, KW ECO:0000213|PeptideAtlas:B4DFA5, ECO:0000213|ProteomicsDB:B4DFA5}; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}. FT DOMAIN 22 60 Yae1_N. {ECO:0000259|Pfam:PF09811}. SQ SEQUENCE 221 AA; 24768 MW; FE6C070D42B3D724 CRC64; MAGSQDIFDA IVMADERFHG EGYREGYEEG SSLGVMEGRQ HGTLHGAKIG SEIGCYQGFA FAWKCLLHSC TTEKDSRKMK VLESLIGMIQ KFPYDDPTYD KLHEDLDKIR GKFKQTGLSP SAVMVRPPSY VELPVTCWCW EAPRCNQKCT DPAARRPDPQ TCASQDRLRC APCTCHQPLA SRYTQHPGLV PLPHHDRQSV PQGPRVVQTD AAARMVEQQT M //