ID B3X2S7_9ENTR Unreviewed; 237 AA. AC B3X2S7; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 10-MAY-2017, entry version 19. DE RecName: Full=Cytolethal distending toxin subunit A {ECO:0000256|PIRNR:PIRNR036516}; DE Short=CDT A {ECO:0000256|PIRNR:PIRNR036516}; GN ORFNames=Sd1012_4316 {ECO:0000313|EMBL:EDX34221.1}; OS Shigella dysenteriae 1012. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; OC Enterobacteriaceae; Shigella. OX NCBI_TaxID=358708 {ECO:0000313|EMBL:EDX34221.1, ECO:0000313|Proteomes:UP000003432}; RN [1] {ECO:0000313|EMBL:EDX34221.1, ECO:0000313|Proteomes:UP000003432} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=1012 {ECO:0000313|EMBL:EDX34221.1, RC ECO:0000313|Proteomes:UP000003432}; RA Rasko D.A., Rosovitz M.J., Brinkley C., Myers G.S.A., Sheshadri R., RA Cer R.Z., Jiang L., Ravel J.; RL Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:EDX34221.1, ECO:0000313|Proteomes:UP000003432} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=1012 {ECO:0000313|EMBL:EDX34221.1, RC ECO:0000313|Proteomes:UP000003432}; RA Rasko D., Rosovitz M., Myers G., Seshadri R., Cer R., Jiang L., RA Ravel J., Fricke W.F., Sebastian Y.; RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: CDTs are cytotoxins. {ECO:0000256|PIRNR:PIRNR036516}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:EDX34221.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AAMJ02000018; EDX34221.1; -; Genomic_DNA. DR RefSeq; WP_000358620.1; NZ_AAMJ02000018.1. DR RefSeq; WP_000358620.1; NZ_AAMJ02000018.1. DR RefSeq; WP_000358620.1; NZ_AAMJ02000018.1. DR EnsemblBacteria; EDX34221; EDX34221; Sd1012_4316. DR PATRIC; 28579363; VBIShiDys19375_3320. DR Proteomes; UP000003432; Unassembled WGS sequence. DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-UniRule. DR GO; GO:0009405; P:pathogenesis; IEA:InterPro. DR InterPro; IPR015957; CDtoxinA. DR InterPro; IPR003558; CDtoxinA/C. DR InterPro; IPR000772; Ricin_B_lectin. DR Pfam; PF03498; CDtoxinA; 1. DR PIRSF; PIRSF036516; CDT_A; 1. DR PRINTS; PR01387; CDTOXINA. DR SUPFAM; SSF50370; SSF50370; 1. DR PROSITE; PS50231; RICIN_B_LECTIN; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000003432}; KW Lectin {ECO:0000256|PIRNR:PIRNR036516}; KW Toxin {ECO:0000256|PIRNR:PIRNR036516}. FT DOMAIN 108 201 Ricin B-type lectin. FT {ECO:0000259|PROSITE:PS50231}. SQ SEQUENCE 237 AA; 25626 MW; 6412BA46E48381FE CRC64; MDKKLIAFLC TLIITGCSNG IGDSPSPPGK NVELVGIPGQ GIAVTSNGAT PTLGTNNTEF PEVSIMSTGG ALLTIWARPV RNWLWGYTPF DSVNFGENRN WKVVDGKDAG TVKFVNVAQG TCMEAFKNGV IHNTCDDNSL SQEFQLLPST NGNVLIRSSA LQTCIRADYL SRTILSPFAF TITLEKCPGA KEETQEMLWA ISPPVRAAKP NLIKPELRPF RPLPIPPHDK PDGMEGV //