ID B3SG81_9BIVA Unreviewed; 93 AA. AC B3SG81; DT 02-SEP-2008, integrated into UniProtKB/TrEMBL. DT 02-SEP-2008, sequence version 1. DT 19-JAN-2010, entry version 9. DE RecName: Full=Cytochrome c oxidase subunit 2; DE Flags: Fragment; GN Name=COII; OS Glebula rotundata. OG Mitochondrion. OC Eukaryota; Metazoa; Mollusca; Bivalvia; Palaeoheterodonta; Unionoida; OC Unionoidea; Unionidae; Lampsilinae; Glebula. OX NCBI_TaxID=152244; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=H1035; RX PubMed=18513440; DOI=10.1186/1471-2148-8-165; RA Chapman E.G., Piontkivska H., Walker J.M., Stewart D.T., Curole J.P., RA Hoeh W.R.; RT "Extreme primary and secondary protein structure variability in the RT chimeric male-transmitted cytochrome c oxidase subunit II protein in RT freshwater mussels: evidence for an elevated amino acid substitution RT rate in the face of domain-specific purifying selection."; RL BMC Evol. Biol. 8:165-165(2008). CC -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory CC chain that catalyzes the reduction of oxygen to water. Subunits 1- CC 3 form the functional core of the enzyme complex. Subunit 2 CC transfers the electrons from cytochrome c via its binuclear copper CC A center to the bimetallic center of the catalytic subunit 1 (By CC similarity). CC -!- COFACTOR: Copper A (By similarity). CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass CC membrane protein (By similarity). CC -!- SIMILARITY: Belongs to the cytochrome c oxidase subunit 2 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EF033284; ABN04255.1; -; Genomic_DNA. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-SubCell. DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-KW. DR GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. DR GO; GO:0005507; F:copper ion binding; IEA:UniProtKB-KW. DR GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro. DR GO; GO:0022900; P:electron transport chain; IEA:UniProtKB-KW. DR GO; GO:0006810; P:transport; IEA:UniProtKB-KW. DR InterPro; IPR001505; Copper_CuA. DR InterPro; IPR008972; Cupredoxin. DR InterPro; IPR002429; Cyt_c_oxidase_su2_C. DR Gene3D; G3DSA:2.60.40.420; Cupredoxin; 1. DR PANTHER; PTHR22888; COX2_C; 1. DR Pfam; PF00116; COX2; 1. DR PRINTS; PR01166; CYCOXIDASEII. DR PROSITE; PS00078; COX2; 1. DR PROSITE; PS50857; COX2_CUA; 1. PE 3: Inferred from homology; KW Copper; Electron transport; Membrane; Metal-binding; Mitochondrion; KW Mitochondrion inner membrane; Respiratory chain; Transmembrane; KW Transport. FT NON_TER 1 1 FT NON_TER 93 93 SQ SEQUENCE 93 AA; 10289 MW; 31787465C7BED645 CRC64; YRLLEVDNRC VLPYGVDSRV LVSSADVIHA WALPSIGVKV DAIPGRINQL GVHLMSSGVM YGQCSEICGV NHSFMPIGLE SVSPEVFYYW LVY //