ID RRAA_CUPTR Reviewed; 165 AA. AC B3R2J3; DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot. DT 02-SEP-2008, sequence version 1. DT 13-JUL-2010, entry version 15. DE RecName: Full=Regulator of ribonuclease activity A; GN Name=rraA; OrderedLocusNames=RALTA_A1769; OS Cupriavidus taiwanensis (strain R1 / LMG 19424) (Ralstonia taiwanensis OS (strain LMG 19424)). OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; OC Burkholderiaceae; Cupriavidus. OX NCBI_TaxID=164546; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=18490699; DOI=10.1101/gr.076448.108; RA Amadou C., Pascal G., Mangenot S., Glew M., Bontemps C., Capela D., RA Carrere S., Cruveiller S., Dossat C., Lajus A., Marchetti M., RA Poinsot V., Rouy Z., Servin B., Saad M., Schenowitz C., Barbe V., RA Batut J., Medigue C., Masson-Boivin C.; RT "Genome sequence of the beta-rhizobium Cupriavidus taiwanensis and RT comparative genomics of rhizobia."; RL Genome Res. 18:1472-1483(2008). CC -!- FUNCTION: Regulator of RNase E/rne, which inhibits the CC endonuclease activity and thereby leads to increase the half-life CC and abundance of RNAs, in those organisms which encode RNase E. CC General modulator of RNA abundance. Does not have any CC methyltransferase activity (By similarity). CC -!- SUBUNIT: Homotrimer. Interacts with RNase E protein and probably CC inhibits its catalytic activity, in those organisms which encode CC RNase E (By similarity). CC -!- SIMILARITY: Belongs to the rraA family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CU633749; CAQ69711.1; -; Genomic_DNA. DR RefSeq; YP_002005776.1; -. DR GeneID; 6453350; -. DR GenomeReviews; CU633749_GR; RALTA_A1769. DR KEGG; cti:RALTA_A1769; -. DR HOGENOM; HBG668175; -. DR OMA; NCALLGD; -. DR ProtClustDB; PRK09372; -. DR GO; GO:0008428; F:ribonuclease inhibitor activity; IEA:InterPro. DR GO; GO:0051252; P:regulation of RNA metabolic process; IEA:InterPro. DR HAMAP; MF_00471; RraA; 1; -. DR InterPro; IPR005493; RNase_E_inh/diMeMenaQ_MeTrfase. DR InterPro; IPR010203; RNase_E_inhibitor_RraA. DR Gene3D; G3DSA:3.50.30.40; RNaseE_inh/diMeMenaQ_MeTrfase; 1. DR Pfam; PF03737; Methyltransf_6; 1. DR SUPFAM; SSF89562; RNaseE_inh/diMeMenaQ_MeTrfase; 1. DR TIGRFAMs; TIGR01935; NOT-MenG; 1. PE 3: Inferred from homology; KW Complete proteome. FT CHAIN 1 165 Regulator of ribonuclease activity A. FT /FTId=PRO_1000125597. SQ SEQUENCE 165 AA; 17532 MW; 5E44558C80B85792 CRC64; MKPVTTDLCD AHEDRLAEGT LRVMAPVFRA FGKQPAFAGP AATLKVFEDN SLVRATLESP GRGRVLVIDG GGSLRCALVG GNLGLLAEKN GWVGIVVNGC IRDTAELDVC DIGIRALAAH PQKSQKRNVG ESEVTVQMPG AVVRPGNWIY VDVDGILVAD DKLER //