ID B3M387_DROAN Unreviewed; 870 AA. AC B3M387; DT 02-SEP-2008, integrated into UniProtKB/TrEMBL. DT 02-SEP-2008, sequence version 1. DT 31-JUL-2019, entry version 75. DE SubName: Full=Uncharacterized protein, isoform A {ECO:0000313|EMBL:EDV43548.1}; DE EC=3.6.1.3 {ECO:0000313|EMBL:EDV43548.1, ECO:0000313|EMBL:KPU80307.1}; DE SubName: Full=Uncharacterized protein, isoform B {ECO:0000313|EMBL:KPU80307.1}; GN Name=Dana\GF16473 {ECO:0000313|EMBL:EDV43548.1}; GN Synonyms=dana_GLEANR_17742 {ECO:0000313|EMBL:KPU80307.1}; GN ORFNames=Dana_GF16473 {ECO:0000313|EMBL:EDV43548.1}, GF16473 GN {ECO:0000313|EMBL:KPU80307.1, ECO:0000313|FlyBase:FBgn0093494}; OS Drosophila ananassae (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7217 {ECO:0000313|EMBL:EDV43548.1, ECO:0000313|Proteomes:UP000007801}; RN [1] {ECO:0000313|EMBL:EDV43548.1, ECO:0000313|Proteomes:UP000007801} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=TSC#14024-0371.13 {ECO:0000313|EMBL:EDV43548.1}, and Tucson RC 14024-0371.13 {ECO:0000313|Proteomes:UP000007801}; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 Genomes Consortium; RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., RA Markow T.A., Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., RA Pollard D.A., Sackton T.B., Larracuente A.M., Singh N.D., Abad J.P., RA Abt D.N., Adryan B., Aguade M., Akashi H., Anderson W.W., RA Aquadro C.F., Ardell D.H., Arguello R., Artieri C.G., Barbash D.A., RA Barker D., Barsanti P., Batterham P., Batzoglou S., Begun D., RA Bhutkar A., Blanco E., Bosak S.A., Bradley R.K., Brand A.D., RA Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C., RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S., RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A., RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., RA Daub J., David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., RA Edwards K., Eickbush T., Evans J.D., Filipski A., Findeiss S., RA Freyhult E., Fulton L., Fulton R., Garcia A.C., Gardiner A., RA Garfield D.A., Garvin B.E., Gibson G., Gilbert D., Gnerre S., RA Godfrey J., Good R., Gotea V., Gravely B., Greenberg A.J., RA Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A., Haerty W., RA Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V., RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., RA Hubisz M.J., Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., RA Jeck W.R., Johnson J., Jones C.D., Jordan W.C., Karpen G.H., RA Kataoka E., Keightley P.D., Kheradpour P., Kirkness E.F., RA Koerich L.B., Kristiansen K., Kudrna D., Kulathinal R.J., Kumar S., RA Kwok R., Lander E., Langley C.H., Lapoint R., Lazzaro B.P., Lee S.J., RA Levesque L., Li R., Lin C.F., Lin M.F., Lindblad-Toh K., Llopart A., RA Long M., Low L., Lozovsky E., Lu J., Luo M., Machado C.A., RA Makalowski W., Marzo M., Matsuda M., Matzkin L., McAllister B., RA McBride C.S., McKernan B., McKernan K., Mendez-Lago M., Minx P., RA Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E., Negre B., RA Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L., RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., RA Pesole G., Phillippy A.M., Ponting C.P., Pop M., Porcelli D., RA Powell J.R., Prohaska S., Pruitt K., Puig M., Quesneville H., RA Ram K.R., Rand D., Rasmussen M.D., Reed L.K., Reenan R., Reily A., RA Remington K.A., Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., RA Rohde C., Rozas J., Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., RA Sanchez-Gracia A., Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., RA Schlenke T., Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., RA Sisneros N.B., Smith C.D., Smith T.F., Spieth J., Stage D.E., RA Stark A., Stephan W., Strausberg R.L., Strempel S., Sturgill D., RA Sutton G., Sutton G.G., Tao W., Teichmann S., Tobari Y.N., RA Tomimura Y., Tsolas J.M., Valente V.L., Venter E., Venter J.C., RA Vicario S., Vieira F.G., Vilella A.J., Villasante A., Walenz B., RA Wang J., Wasserman M., Watts T., Wilson D., Wilson R.K., Wing R.A., RA Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G., Yamamoto D., RA Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E., Zhang P., RA Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J., RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., RA An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., RA Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Blye J., RA Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A., RA Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M., RA Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G., RA DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M., RA Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S., RA Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D., RA Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T., RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B., RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L., RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D., RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., RA LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., RA Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V., RA Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J., RA Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V., RA Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T., RA Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B., RA Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P., RA Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C., RA Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L., RA Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N., RA Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T., RA Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T., RA Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J., RA Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A., RA Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C., RA Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). RN [2] {ECO:0000313|EMBL:EDV43548.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=TSC#14024-0371.13 {ECO:0000313|EMBL:EDV43548.1}; RX PubMed=18057021; DOI=10.1093/bioinformatics/btm542; RA Zimin A.V., Smith D.R., Sutton G., Yorke J.A.; RT "Assembly reconciliation."; RL Bioinformatics 24:42-45(2008). RN [3] {ECO:0000313|EMBL:EDV43548.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=TSC#14024-0371.13 {ECO:0000313|EMBL:EDV43548.1}; RG FlyBase; RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases. RN [4] {ECO:0000313|EMBL:KPU80307.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=TSC#14024-0371.13 {ECO:0000313|EMBL:KPU80307.1}; RA Gilbert D.G.; RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CH902617; EDV43548.1; -; Genomic_DNA. DR EMBL; CH902617; KPU80307.1; -; Genomic_DNA. DR RefSeq; XP_001954987.1; XM_001954951.2. DR RefSeq; XP_014765995.1; XM_014910509.1. DR STRING; 7217.FBpp0119665; -. DR EnsemblMetazoa; FBtr0121173; FBpp0119665; FBgn0093494. DR EnsemblMetazoa; FBtr0388381; FBpp0348094; FBgn0093494. DR GeneID; 6499269; -. DR KEGG; dan:Dana_GF16473; -. DR FlyBase; FBgn0093494; Dana\GF16473. DR eggNOG; KOG0057; Eukaryota. DR eggNOG; COG5265; LUCA. DR InParanoid; B3M387; -. DR KO; K05661; -. DR OMA; VLALPCK; -. DR OrthoDB; 248727at2759; -. DR Proteomes; UP000007801; Unassembled WGS sequence. DR Bgee; FBgn0093494; Expressed in 1 organ(s), highest expression level in adult organism. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005774; C:vacuolar membrane; IEA:EnsemblMetazoa. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0016887; F:ATPase activity; IEA:UniProtKB-EC. DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IEA:InterPro. DR GO; GO:0046686; P:response to cadmium ion; IEA:EnsemblMetazoa. DR Gene3D; 1.20.1560.10; -; 1. DR InterPro; IPR003593; AAA+_ATPase. DR InterPro; IPR011527; ABC1_TM_dom. DR InterPro; IPR036640; ABC1_TM_sf. DR InterPro; IPR003439; ABC_transporter-like. DR InterPro; IPR017871; ABC_transporter_CS. DR InterPro; IPR032410; MTABC_N. DR InterPro; IPR027417; P-loop_NTPase. DR InterPro; IPR039421; Type_I_exporter. DR PANTHER; PTHR24221; PTHR24221; 1. DR Pfam; PF00664; ABC_membrane; 1. DR Pfam; PF00005; ABC_tran; 1. DR Pfam; PF16185; MTABC_N; 1. DR SMART; SM00382; AAA; 1. DR SUPFAM; SSF52540; SSF52540; 1. DR SUPFAM; SSF90123; SSF90123; 1. DR PROSITE; PS50929; ABC_TM1F; 1. DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1. DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1. PE 4: Predicted; KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00434}; KW Complete proteome {ECO:0000313|Proteomes:UP000007801}; KW Hydrolase {ECO:0000313|EMBL:EDV43548.1}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00434}; KW Reference proteome {ECO:0000313|Proteomes:UP000007801}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 30 47 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 67 86 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 98 119 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 135 154 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 174 192 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 243 269 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 289 309 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 366 389 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 395 415 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 486 504 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 250 540 ABC transmembrane type-1. FT {ECO:0000259|PROSITE:PS50929}. FT DOMAIN 574 808 ABC transporter. {ECO:0000259|PROSITE: FT PS50893}. FT NP_BIND 607 614 ATP. {ECO:0000256|PROSITE-ProRule: FT PRU00434}. FT REGION 813 870 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 813 827 Polar. {ECO:0000256|SAM:MobiDB-lite}. SQ SEQUENCE 870 AA; 98239 MW; E435A9B996285D46 CRC64; MLYCPPNVTL SEVWTNHGIS HCFMDTVGPA VYGGFLLLFG CIQLLMYRKY ATRITDPTQF SRSRLYAVQL FLLLLLPVLA LIRFFLNARI YPDSTVYGYM IFSTCVVCIS YPFSICLIVK ERFYQLPSVP TRGHGLILLL FWTLAFINES LAFINLRHED WWFHLKSNKD EIEMGLFVTR FFCSLLIFVL GLKAPGIMAP YNPHQRLDDS SSESQGAPTG SAFRNGWRKL RTLFPYLWPK KDLALQLAVI FCIILLFAGR VIKLFLPIYR KKLVDSLTIE PIIFRWDFVL IYVALSFLQG GGTGSMGLFN NLRTFLWIRV QQYTTREIEI ELFRHLHQLS LRWHLHRKTG EVLRVMDRGT DSINNLLNYI VFSITPTILD LLVAVAFFIY AFNWWFGLIV FLTMFLYIAS TIAITEWRTK YQRRMNLADN EQRARSVDSL LNFETVKYYG AEHYEVDCYR EAILKYQKEE FLSMLTLNML NTAQNIILCL GLLAGSLLCV YLVVHHQTLT VGDFVLFSTY LMELYMPLNW FGTYYRAIQK NFVDMENMFD LLREEEEIVD APGSSPLLTA GGSIEFSNVT FGYSPEKLVL RNVSFTVPAG KTVAIVGPSG AGKSTIMRLL FRFYDVQTGA ILIDGQNIKL VQQQSLRQAI GVVPQDTVLF NNTIFYNIEY AKLGASPDAV YEAARAADIH EKILSFPESY ETKVGERGLR LSGGEKQRVA IARTLLKAPI IVLLDEATSA LDTHTERNIQ AALARVCANR TTIIVAHRLS TIIHADEILV LKEGNIVERG RHDQLVLRDD GVYADMWQQQ LKNLDSDQSG SDNGDAGTDS GSEKRSAGGK GPGPAAGPSG AGFGGGGAHF RAGHAHGGAR //