ID B3KUM4_HUMAN Unreviewed; 145 AA. AC B3KUM4; DT 02-SEP-2008, integrated into UniProtKB/TrEMBL. DT 02-SEP-2008, sequence version 1. DT 06-JUL-2016, entry version 43. DE RecName: Full=Peptidylprolyl isomerase {ECO:0000256|RuleBase:RU363014}; DE EC=5.2.1.8 {ECO:0000256|RuleBase:RU363014}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG53486.1}; RN [1] {ECO:0000313|EMBL:BAG53486.1} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Testis {ECO:0000313|EMBL:BAG53486.1}; RX PubMed=14702039; DOI=10.1038/ng1285; RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T., Nomura Y., RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.; RT "Complete sequencing and characterization of 21,243 full-length human RT cDNAs."; RL Nat. Genet. 36:40-45(2004). CC -!- CATALYTIC ACTIVITY: Peptidylproline (omega=180) = peptidylproline CC (omega=0). {ECO:0000256|RuleBase:RU363014}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK097558; BAG53486.1; -; mRNA. DR UniGene; Hs.465849; -. DR ProteinModelPortal; B3KUM4; -. DR STRING; 9606.ENSP00000247970; -. DR PaxDb; B3KUM4; -. DR PeptideAtlas; B3KUM4; -. DR PRIDE; B3KUM4; -. DR eggNOG; KOG3259; Eukaryota. DR eggNOG; COG0760; LUCA. DR HOGENOM; HOG000275331; -. DR HOVERGEN; HBG002101; -. DR SignaLink; B3KUM4; -. DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW. DR InterPro; IPR000297; PPIase_PpiC. DR InterPro; IPR023058; PPIase_PpiC_CS. DR InterPro; IPR001202; WW_dom. DR Pfam; PF00639; Rotamase; 1. DR Pfam; PF00397; WW; 1. DR SMART; SM00456; WW; 1. DR SUPFAM; SSF51045; SSF51045; 1. DR PROSITE; PS01096; PPIC_PPIASE_1; 1. DR PROSITE; PS50198; PPIC_PPIASE_2; 1. DR PROSITE; PS01159; WW_DOMAIN_1; 1. DR PROSITE; PS50020; WW_DOMAIN_2; 1. PE 2: Evidence at transcript level; KW Isomerase {ECO:0000256|RuleBase:RU363014, KW ECO:0000313|EMBL:BAG53486.1}; KW Rotamase {ECO:0000256|RuleBase:RU363014}. FT DOMAIN 5 39 WW. {ECO:0000259|PROSITE:PS50020}. FT DOMAIN 52 128 PpiC. {ECO:0000259|PROSITE:PS50198}. SQ SEQUENCE 145 AA; 16130 MW; CB9B67B9CD5EA9BD CRC64; MADEEKLPPG WEKRMSRGSG RVYYFNHITN ASQWERPSGN SSSGGKNGQG EPARVRCSHL LVKHSRSRRP SSWRQEKITR TKEEALELIN GYIQKIKSGE EDFESLASQF SDCSSAKARG DLGAFSRGAQ GMGLTRLGDP YHPEG //