ID B3KTV0_HUMAN Unreviewed; 621 AA. AC B3KTV0; DT 02-SEP-2008, integrated into UniProtKB/TrEMBL. DT 02-SEP-2008, sequence version 1. DT 29-SEP-2021, entry version 54. DE SubName: Full=cDNA FLJ38781 fis, clone LIVER2000216, highly similar to HEAT SHOCK COGNATE 71 kDa PROTEIN {ECO:0000313|EMBL:BAG53212.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG53212.1}; RN [1] {ECO:0000313|EMBL:BAG53212.1} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Liver {ECO:0000313|EMBL:BAG53212.1}; RX PubMed=14702039; DOI=10.1038/ng1285; RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., RA Tanase T., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., RA Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., RA Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., RA Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., RA Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., RA Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., RA Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., RA Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., RA Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., RA Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., RA Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., RA Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., RA Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., RA Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., RA Sugano S.; RT "Complete sequencing and characterization of 21,243 full-length human RT cDNAs."; RL Nat. Genet. 36:40-45(2004). CC -!- SIMILARITY: Belongs to the heat shock protein 70 family. CC {ECO:0000256|ARBA:ARBA00007381, ECO:0000256|RuleBase:RU003322}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK096100; BAG53212.1; -; mRNA. DR IntAct; B3KTV0; 1. DR PeptideAtlas; B3KTV0; -. DR PRIDE; B3KTV0; -. DR OMA; IFREDRC; -. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR Gene3D; 1.20.1270.10; -; 1. DR Gene3D; 2.60.34.10; -; 1. DR InterPro; IPR043129; ATPase_NBD. DR InterPro; IPR018181; Heat_shock_70_CS. DR InterPro; IPR029048; HSP70_C_sf. DR InterPro; IPR029047; HSP70_peptide-bd_sf. DR InterPro; IPR013126; Hsp_70_fam. DR PANTHER; PTHR19375; PTHR19375; 2. DR Pfam; PF00012; HSP70; 2. DR SUPFAM; SSF100920; SSF100920; 1. DR SUPFAM; SSF100934; SSF100934; 1. DR SUPFAM; SSF53067; SSF53067; 2. DR PROSITE; PS00297; HSP70_1; 1. DR PROSITE; PS00329; HSP70_2; 1. DR PROSITE; PS01036; HSP70_3; 1. PE 2: Evidence at transcript level; KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003322}; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, KW ECO:0000256|RuleBase:RU003322}; KW Stress response {ECO:0000313|EMBL:BAG53212.1}. FT REGION 589..621 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COILED 487..510 FT /evidence="ECO:0000256|SAM:Coils" SQ SEQUENCE 621 AA; 67980 MW; 42BB40ADED19790F CRC64; MSKGPAVGID LGTTYSCVGV FQHGKVEIIA NDQGNRTTPS YVAFTDTERL IGDAAKNQVA MNPTNTVMVV NDAGRPKVQV EYKGETKSFY PEEVSSMVLT KMKEIAEAYL GKTVTNAVVT VPAYFNDSQR QATKDAGTIA GLNVLRIINE PTAAAIAYGL DKKVGAERNV LIFDLGGGTF DVSILTIEDG IFEVKSTAGD THLGGEDFDN RMVNHFIAEF KRKHKKDISE NKRAVRRLRT ACERAKRTLS SSTQASIEID SLYEGIDFYT SITRARFEEL NADLFRGTLD PVEKALRDAK LDKSQIHDIV LVGGSTRIPK IQKLLQDFFN GKELNKSINP DEAVAYGAAV QAAILSGDKS ENVQDLLLLD VTPLSLGIET AGGVMTVLIK RNTTIPTKQT QTFTTYSDNQ PGVLIQVYEG ERAMTKDNNL LGKFELTGIP PAPRGVPQIE VTFDIDANGI LNVSAVDKST GKENKITITN DKGRLSKEDI ERMVQEAEKY KAEDEKQRDK VSSKNSLESY AFNMKATVED EKLQGKINDE DKQKILDKCN EIINWLDKNQ TAEKEEFEHQ QKELEKVCNP IITKLYQSAG GMPGGMPGGF PGGGAPPSGG ASSRPTIEEV D //