ID B3GJG4_9BIVA Unreviewed; 206 AA. AC B3GJG4; DT 22-JUL-2008, integrated into UniProtKB/TrEMBL. DT 22-JUL-2008, sequence version 1. DT 28-NOV-2012, entry version 18. DE RecName: Full=Cytochrome c oxidase subunit 1; DE EC=1.9.3.1; DE Flags: Fragment; GN Name=COI; OS Cristaria plicata. OG Mitochondrion. OC Eukaryota; Metazoa; Lophotrochozoa; Mollusca; Bivalvia; OC Palaeoheterodonta; Unionoida; Unionoidea; Unionidae; Anodontinae; OC Cristaria. OX NCBI_TaxID=165446; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Mantle; RA Jia M.J., Li J.L.; RT "Sequence Analysis of Mitochondrial Cytochrome Oxidase Subunit (COI) RT Gene of Cristaria plicata from the Lower Yangtze Region."; RL Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory CC chain that catalyzes the reduction of oxygen to water. Subunits 1- CC 3 form the functional core of the enzyme complex. CO I is the CC catalytic subunit of the enzyme. Electrons originating in CC cytochrome c are transferred via the copper A center of subunit 2 CC and heme A of subunit 1 to the bimetallic center formed by heme A3 CC and copper B (By similarity). CC -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4 CC ferricytochrome c + 2 H(2)O. CC -!- PATHWAY: Energy metabolism; oxidative phosphorylation. CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass CC membrane protein (By similarity). CC -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EU698901; ACD76922.1; -; Genomic_DNA. DR ProteinModelPortal; B3GJG4; -. DR UniPathway; UPA00705; -. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. DR GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. DR GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:EC. DR GO; GO:0009055; F:electron carrier activity; IEA:InterPro. DR GO; GO:0020037; F:heme binding; IEA:InterPro. DR GO; GO:0005506; F:iron ion binding; IEA:InterPro. DR GO; GO:0009060; P:aerobic respiration; IEA:InterPro. DR GO; GO:0022900; P:electron transport chain; IEA:UniProtKB-KW. DR Gene3D; 1.20.210.10; COX1; 1. DR InterPro; IPR000883; Cyt_c_Oxase_su1. DR InterPro; IPR023616; Cyt_c_Oxase_su1_dom. DR PANTHER; PTHR10422; PTHR10422; 1. DR Pfam; PF00115; COX1; 1. DR PRINTS; PR01165; CYCOXIDASEI. DR SUPFAM; SSF81442; COX1; 1. DR PROSITE; PS50855; COX1; 1. PE 3: Inferred from homology; KW Copper; Electron transport; Heme; Iron; Membrane; Metal-binding; KW Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; KW Respiratory chain; Transmembrane; Transport. FT NON_TER 1 1 FT NON_TER 206 206 SQ SEQUENCE 206 AA; 21901 MW; F2E38B6A644BBBC6 CRC64; LALSLLIRAE LGQPGSLLGD DQLYNVIVTA HAFMMIFFLV MPMMIGGFGN WLIPLMIGAP DMAFPRLNNL SFWLLVPALF LLLSSSLVES GVGTGWTVYP PLSGNVAHSG ASVDLAIFSL HLAGASSILG AINFISTVGN MRSPGLVAER IPLFVWAVTV TAALLVAALP VLAGAITMLL TDRNLNTSFF DPTGGGDPIL YMHLFW //