ID B3F6B5_BOVIN Unreviewed; 264 AA. AC B3F6B5; DT 22-JUL-2008, integrated into UniProtKB/TrEMBL. DT 22-JUL-2008, sequence version 1. DT 05-OCT-2010, entry version 18. DE RecName: Full=Major prion protein; GN Name=PRNP; OS Bos taurus (Bovine). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; OC Pecora; Bovidae; Bovinae; Bos. OX NCBI_TaxID=9913; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=50-0039-3; RX PubMed=18096956; RA Brunelle B.W., Kehrli M.E.Jr., Stabel J.R., Spurlock D.M., RA Hansen L.B., Nicholson E.M.; RT "Short communication: Allele, genotype, and haplotype data for bovine RT spongiform encephalopathy-resistance polymorphisms from healthy US RT Holstein cattle."; RL J. Dairy Sci. 91:338-342(2008). CC -!- SIMILARITY: Belongs to the prion family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EF626285; ABU98047.1; -; Genomic_DNA. DR IPI; IPI00702852; -. DR STRING; B3F6B5; -. DR Ensembl; ENSBTAT00000040292; ENSBTAP00000043233; ENSBTAG00000027937. DR HOVERGEN; HBG008260; -. DR InParanoid; B3F6B5; -. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW. DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro. DR GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. DR GO; GO:0007165; P:signal transduction; IEA:InterPro. DR InterPro; IPR001610; PAC. DR InterPro; IPR000817; Prion. DR InterPro; IPR022416; Prion/Doppel_prot_b-ribbon_dom. DR Gene3D; G3DSA:1.10.790.10; Prion; 1. DR PANTHER; PTHR11522; Prion; 1. DR Pfam; PF00377; Prion; 1. DR PRINTS; PR00341; PRION. DR SMART; SM00086; PAC; 1. DR SMART; SM00157; PRP; 1. DR SUPFAM; SSF54098; Prion; 1. DR PROSITE; PS00291; PRION_1; 1. DR PROSITE; PS00706; PRION_2; 1. PE 3: Inferred from homology; KW Amyloid; Cell membrane; Membrane; Prion; Repeat. SQ SEQUENCE 264 AA; 28668 MW; 751470504574A54C CRC64; MVKSHIGSWI LVLFVAMWSD VGLCKKRPKP GGGWNTGGSR YPGQGSPGGN RYPPQGGGXW GQPHGGGWGQ PHGGGWGQPH GGGWGQPHGG GWGQPHGGGG WGQGGTHGQW NKPSKPKTNM KHVAGAAAAG AVVGGLGGYM LGSAMSRPLI HFGSDYEDRY YRENMHRYPN QVYYRPVDQY SNQNNFVHDC VNITVKEHTV TTTTKGENFT ETDIKMMERV VEQMCITQYQ RESQAYYQRG ASVILFSSPP VILLISFLIF LIVG //