ID B3EAK5_GEOLS Unreviewed; 535 AA. AC B3EAK5; DT 22-JUL-2008, integrated into UniProtKB/TrEMBL. DT 22-JUL-2008, sequence version 1. DT 24-MAR-2009, entry version 9. DE SubName: Full=CTP synthase; DE EC=6.3.4.2; DE Flags: Precursor; GN OrderedLocusNames=Glov_1727; OS Geobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ). OC Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales; OC Geobacteraceae; Geobacter. OX NCBI_TaxID=398767; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., RA Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Meincke L., RA Brettin T., Detter J.C., Han C., Tapia R., Kuske C.R., Schmutz J., RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Sung Y., RA Fletcher K.E., Ritalahti K.M., Loeffler F.E., Richardson P.; RT "Complete sequence of chromosome of Geobacter lovleyi SZ."; RL Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Catalyzes the ATP-dependent amination of UTP to CTP with CC either L-glutamine or ammonia as the source of nitrogen (By CC Similarity).. CC -!- CATALYTIC ACTIVITY: ATP + UTP + NH(3) = ADP + phosphate + CTP. CC -!- SUBUNIT: Pyrimidine metabolism; CTP biosynthesis via de novo CC pathway; CTP from UDP: step 2/2 (By Similarity).. CC -!- SIMILARITY: Contains 1 glutamine amidotransferase type-1 domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP001089; ACD95443.1; -; Genomic_DNA. DR RefSeq; YP_001951963.1; -. DR GeneID; 6369258; -. DR GenomeReviews; CP001089_GR; Glov_1727. DR KEGG; glo:Glov_1727; -. DR GO; GO:0003883; F:CTP synthase activity; IEA:InterPro. DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW. DR GO; GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:InterPro. DR InterPro; IPR004468; CTP_synthase. DR InterPro; IPR017456; CTP_synthase_N. DR InterPro; IPR017926; GATASE_1. DR InterPro; IPR000991; GATase_class1_C. DR PANTHER; PTHR11550; PyrG_synth; 1. DR Pfam; PF06418; CTP_synth_N; 1. DR Pfam; PF00117; GATase; 1. DR TIGRFAMs; TIGR00337; PyrG; 1. DR PROSITE; PS51273; GATASE_TYPE_1; 1. PE 3: Inferred from homology; KW Complete proteome; Glutamine amidotransferase; Ligase; KW Pyrimidine biosynthesis; Signal. FT SIGNAL 1 22 Potential. FT CHAIN 23 535 Potential. FT /FTId=PRO_5000374670. SQ SEQUENCE 535 AA; 59767 MW; B86BADC1F55A3205 CRC64; MKTKFIFITG GVVSSIGKGL AAASLGALLE SRGLRVTMQK LDPYINVDPG TMSPFQHGEV FVTDDGAETD LDLGHYERYT SARLSKKSNF TTGQVYFSVI DKERRGDYLG GTVQVIPHIT DEIKSKIIEN AKGADVAIVE VGGTVGDIES LPFLEAIRQF RFDRGAGNTL YVHVTLVPYI RTAGEMKTKP TQHSVMELRK IGIQPDILLC RCDRELPQDM KKKISLFCNV EESCVIPSVD SEHIYAVPLA LNKERLDEQV VEKLNIWTKQ PDLTPWQDVV ETLRHPSHGE VRIAIVGKYV NLTESYKSLA EALTHGGIAN DCRVYLKYVD AEKIEENGVE GWLDDVDGVL VPGGFGERGT EGKVLAIEYA RTRQIPFFGI CLGMQMAAIE FARNVCGLAK ACSTEFKNDC KEPVIHLMEE QKSVNKKGGT MRLGACPCTV TKGTKAFDAY NEADISERHR HRYEFNNTYR ELMTTKGLVL SGINQQKDLV EIIELPDHPW FLACQFHPEF KSKPLVPHPL FRAFIGASLT HRNQR //