ID B3DHC5_DANRE Unreviewed; 255 AA. AC B3DHC5; DT 22-JUL-2008, integrated into UniProtKB/TrEMBL. DT 22-JUL-2008, sequence version 1. DT 11-DEC-2019, entry version 99. DE SubName: Full=Apolipoprotein A-IV b, tandem duplicate 2 {ECO:0000313|Ensembl:ENSDARP00000093966}; DE SubName: Full=Zgc:194131 {ECO:0000313|EMBL:AAI62715.1}; GN Name=apoa4b.2 {ECO:0000313|Ensembl:ENSDARP00000093966, GN ECO:0000313|ZFIN:ZDB-GENE-030131-3143}; GN ORFNames=zgc:194131 {ECO:0000313|EMBL:AAI62715.1}; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955 {ECO:0000313|EMBL:AAI62715.1}; RN [1] {ECO:0000313|EMBL:AAI62715.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RG NIH - Zebrafish Gene Collection (ZGC) project; RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSDARP00000093966} RP IDENTIFICATION. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000093966}; RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. RN [3] {ECO:0000313|Ensembl:ENSDARP00000093966, ECO:0000313|Proteomes:UP000000437} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000093966, RC ECO:0000313|Proteomes:UP000000437}; RX PubMed=23594743; DOI=10.1038/nature12111; RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J., RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.; RT "The zebrafish reference genome sequence and its relationship to the human RT genome."; RL Nature 496:498-503(2013). CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|SAAS:SAAS00143437}. CC -!- SIMILARITY: Belongs to the apolipoprotein A1/A4/E family. CC {ECO:0000256|SAAS:SAAS00598075}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BX004983; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; BC162715; AAI62715.1; -; mRNA. DR EMBL; BC162716; AAI62716.1; -; mRNA. DR RefSeq; NP_001122230.1; NM_001128758.1. DR STRING; 7955.ENSDARP00000114649; -. DR Ensembl; ENSDART00000103190; ENSDARP00000093966; ENSDARG00000020866. DR Ensembl; ENSDART00000142168; ENSDARP00000114649; ENSDARG00000020866. DR GeneID; 570354; -. DR KEGG; dre:570354; -. DR CTD; 570354; -. DR ZFIN; ZDB-GENE-030131-3143; apoa4b.2. DR eggNOG; ENOG410IKU1; Eukaryota. DR eggNOG; ENOG41119VI; LUCA. DR GeneTree; ENSGT00950000182929; -. DR HOGENOM; HOG000063678; -. DR OMA; EPYTENM; -. DR OrthoDB; 1299087at2759; -. DR TreeFam; TF334458; -. DR Proteomes; UP000000437; Chromosome 16. DR Bgee; ENSDARG00000020866; Expressed in 22 organ(s), highest expression level in intestine. DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. DR GO; GO:0008289; F:lipid binding; IEA:InterPro. DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW. DR GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro. DR InterPro; IPR000074; ApoA_E. DR Pfam; PF01442; Apolipoprotein; 1. PE 1: Evidence at protein level; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Lipid transport {ECO:0000256|SAAS:SAAS00143435}; KW Proteomics identification {ECO:0000213|PeptideAtlas:B3DHC5}; KW Reference proteome {ECO:0000313|Proteomes:UP000000437}; KW Secreted {ECO:0000256|SAAS:SAAS00143438}; Signal {ECO:0000256|SAM:SignalP}; KW Transport {ECO:0000256|SAAS:SAAS00143436}. FT SIGNAL 1..17 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 18..255 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5015087202" FT COILED 153..177 FT /evidence="ECO:0000256|SAM:Coils" SQ SEQUENCE 255 AA; 29384 MW; 94E4385541269D82 CRC64; MKVLVVFALA VFTGCQANLF YADEPKPQLE QLTDAFWSYV SKATQTAEET VKMIRESQLG QEVNERLTQS ADMASEYAVV LKKQVDPLTE ELMNKITKET EVLRERLGQD LINVREKLEP YADNMKSQIQ QRVEELRAAM APYADSLDSE TLKATLLQKS EELRGNLEQS VKELQVQLEP YTAELKEKVD QHLQEFQKTV TPLTEDLQVQ IRERAQMVQQ SLTPYAEDLK EKLDPYAQNL KDQLASLYES YTKRN //