ID B3DGG4_DANRE Unreviewed; 800 AA. AC B3DGG4; DT 22-JUL-2008, integrated into UniProtKB/TrEMBL. DT 22-JUL-2008, sequence version 1. DT 28-NOV-2012, entry version 37. DE SubName: Full=Cadherin 11, osteoblast; DE SubName: Full=Cdh11 protein; DE SubName: Full=Uncharacterized protein; GN Name=cdh11; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Pooled; RG NIH - Zebrafish Gene Collection (ZGC) project; RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tuebingen; RG The Danio rerio Sequencing Project at the Sanger Institute; RT "The genomic sequence of Danio rerio."; RL Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases. RN [3] RP IDENTIFICATION. RC STRAIN=Tuebingen; RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- FUNCTION: Cadherins are calcium dependent cell adhesion proteins CC (By similarity). CC -!- SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane CC protein (By similarity). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CT025913; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; BC162388; AAI62388.1; -; mRNA. DR EMBL; BC162403; AAI62403.1; -; mRNA. DR EMBL; BC163442; AAI63442.1; -; mRNA. DR IPI; IPI00855305; -. DR RefSeq; NP_571289.1; NM_131214.1. DR UniGene; Dr.251; -. DR Ensembl; ENSDART00000002279; ENSDARP00000006449; ENSDARG00000021442. DR GeneID; 30461; -. DR KEGG; dre:30461; -. DR CTD; 1009; -. DR ZFIN; ZDB-GENE-980526-170; cdh11. DR GeneTree; ENSGT00680000099905; -. DR HOGENOM; HOG000231252; -. DR HOVERGEN; HBG005217; -. DR KO; K06803; -. DR OMA; HIDPKFI; -. DR NextBio; 20806855; -. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW. DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro. DR GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro. DR GO; GO:0048840; P:otolith development; IMP:ZFIN. DR Gene3D; 2.60.40.60; Cadherin; 5. DR InterPro; IPR002126; Cadherin. DR InterPro; IPR015919; Cadherin-like. DR InterPro; IPR020894; Cadherin_CS. DR InterPro; IPR000233; Cadherin_cytoplasmic-dom. DR Pfam; PF00028; Cadherin; 5. DR Pfam; PF01049; Cadherin_C; 1. DR PRINTS; PR00205; CADHERIN. DR SMART; SM00112; CA; 5. DR SUPFAM; SSF49313; Cadherin; 5. DR PROSITE; PS00232; CADHERIN_1; 3. DR PROSITE; PS50268; CADHERIN_2; 5. PE 2: Evidence at transcript level; KW Calcium; Cell adhesion; Cell membrane; Complete proteome; Membrane; KW Reference proteome; Repeat; Transmembrane; Transmembrane helix. SQ SEQUENCE 800 AA; 88933 MW; 25B84ABE5598810B CRC64; MWEGLRLQVF FLCLGAALWS AAAAATHRGS GPRERGHRRH LSLHRHRERG KEGQVLHRSK RGWVWNQFFV IEEYTGPDPV LVGRLHSDVD SGDGNIKYIL SGEGAGTIFV IDDKTGNIHA TKTLDREEQA QYTLTAQAVA RDTNKPLEPP SEFIVKVQDI NDNPPEFLHG PYYARVAEMS NVGTSVIKVT ATDADDPTYG NSARLVYSIL QGQPYFSVEP QTGIIRTALP NMDREARQEY DVVIQAKDMG GHMGGLSGTT QVKITLTDVN DNPPKFAQGV YAMAVSEDKV PGEEVGRLKA RDPDLAENGL VDYRILEGDG MNYFEITKDS ETQEAVIKLK KPVDFETKRS YTLKVEATNT HVDPRFIAWG PYKDTTIVKI SVEDADEPPT FMAPSYNFEV EENAPAGTLV GRVHAKDTDM MNNPIRYMIP HYTDLEEFFT INPEDGIIKT TRPLDREAQA WHNISVSATE IGGHHQDAKV RVNIKVKDVN DNAPEFATQN EVLVCENVNP GKLIETVSAT DKDEMAHRQH FHFSLAPEVA NNHSFSLKDN RDSTASIFVI RKGFSRMTQD IYHLPIEIND NGVPPMSSTN TLIIRVCSCD SKDTILSCNV EPFILTAGLS TGALIAILAC IVILLAIVVL FVALRRQKKE PLIVFEEEDI RENIITYDDE GGGEEDTEAF DIATLQNPDG ANGFLPRKDM KPELQYGMRP GLRPIGNSVD VDDFIKTRIS DADNDPTAPP YDSIQIYGYE GRGSIAGSLS SLESVTTDSD LDYDYLQSWG PRFKKLADLY GTKDSVDDNS //