ID B3CJD3_HUMAN Unreviewed; 267 AA. AC B3CJD3; DT 22-JUL-2008, integrated into UniProtKB/TrEMBL. DT 22-JUL-2008, sequence version 1. DT 11-JUL-2012, entry version 28. DE SubName: Full=V-myc myelocytomatosis viral oncogene homolog; DE Flags: Fragment; GN Name=MYC; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=16697040; DOI=10.1016/j.leukres.2006.03.026; RA Burmeister T., Molkentin M., Schwartz S., Goekbuget N., Hoelzer D., RA Thiel E., Reinhardt R.; RT "Erroneous class switching and false VDJ recombination: the spectrum RT of t(8;14)/MYC-IGH translocations in high-grade lymphoma/mature B-cell RT lymphoblastic leukemia."; RL Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AM287181; CAL18368.1; -; Genomic_DNA. DR IPI; IPI00977922; -. DR STRING; B3CJD3; -. DR HOVERGEN; HBG000472; -. DR GO; GO:0030424; C:axon; IEA:Compara. DR GO; GO:0005737; C:cytoplasm; IEA:Compara. DR GO; GO:0016604; C:nuclear body; IEA:Compara. DR GO; GO:0005730; C:nucleolus; IEA:Compara. DR GO; GO:0005819; C:spindle; IEA:Compara. DR GO; GO:0003690; F:double-stranded DNA binding; IEA:Compara. DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:Compara. DR GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Compara. DR GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Compara. DR GO; GO:0008633; P:activation of pro-apoptotic gene products; IEA:Compara. DR GO; GO:0006309; P:apoptotic DNA fragmentation; IEA:Compara. DR GO; GO:0001783; P:B cell apoptotic process; IEA:Compara. DR GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Compara. DR GO; GO:0035690; P:cellular response to drug; IEA:Compara. DR GO; GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IEA:Compara. DR GO; GO:0006006; P:glucose metabolic process; IEA:Compara. DR GO; GO:0008629; P:induction of apoptosis by intracellular signals; IEA:Compara. DR GO; GO:0042474; P:middle ear morphogenesis; IEA:Compara. DR GO; GO:0032091; P:negative regulation of protein binding; IEA:Compara. DR GO; GO:0008634; P:negative regulation of survival gene product expression; IEA:Compara. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara. DR GO; GO:0043473; P:pigmentation; IEA:Compara. DR GO; GO:0002904; P:positive regulation of B cell apoptotic process; IEA:Compara. DR GO; GO:0090096; P:positive regulation of metanephric cap mesenchymal cell proliferation; IEA:Compara. DR GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara. DR GO; GO:0016485; P:protein processing; IEA:Compara. DR GO; GO:0007346; P:regulation of mitotic cell cycle; IEA:Compara. DR GO; GO:0001836; P:release of cytochrome c from mitochondria; IEA:Compara. DR GO; GO:0043279; P:response to alkaloid; IEA:Compara. DR GO; GO:0009314; P:response to radiation; IEA:Compara. DR GO; GO:0048705; P:skeletal system morphogenesis; IEA:Compara. DR GO; GO:0006366; P:transcription from RNA polymerase II promoter; IEA:Compara. DR GO; GO:0006352; P:transcription initiation, DNA-dependent; IEA:Compara. DR GO; GO:0016055; P:Wnt receptor signaling pathway; IEA:Compara. DR InterPro; IPR002418; Tscrpt_reg_Myc. DR InterPro; IPR012682; Tscrpt_reg_Myc_N. DR Pfam; PF01056; Myc_N; 1. DR PIRSF; PIRSF001705; Myc_protein; 1. DR PRINTS; PR00044; LEUZIPPRMYC. PE 4: Predicted; FT NON_TER 1 1 SQ SEQUENCE 267 AA; 29034 MW; 25C8358C773B1491 CRC64; MDFFRVVENH QPPATMPLNV SFTNRNYDLD YDSVQPYFYC DEEENFYQQQ QQSELQPPAP SEDIWKKFEL LPTPPLSPSR RSGLCSPSYV AVTPFSLRGD NDGGGGSFST ADQLEMVTEL LGGDMVNQSF ICDPDDETFI KNIIIQDCMW SGFSAAAKLV SEKLASYQAA RKDSGSPNPA RGHSVCSTSS LYLQDLSAAA SECIDPSVVF PYPLNDSSSP KSCASQDSSA FSPSSDSLLS STESSPQGSP EPLVLHEETP PTTSSDS //