ID B3CJB2_HUMAN Unreviewed; 252 AA. AC B3CJB2; DT 22-JUL-2008, integrated into UniProtKB/TrEMBL. DT 22-JUL-2008, sequence version 1. DT 02-OCT-2024, entry version 68. DE SubName: Full=V-myc myelocytomatosis viral oncogene homolog {ECO:0000313|EMBL:CAL18347.1}; DE Flags: Fragment; GN Name=MYC {ECO:0000313|EMBL:CAL18347.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:CAL18347.1}; RN [1] {ECO:0000313|EMBL:CAL18347.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=23673335; DOI=10.1016/j.molonc.2013.04.006; RA Burmeister T., Molkentin M., Schwartz S., Gokbuget N., Hoelzer D., RA Thiel E., Reinhardt R.; RT "Erroneous class switching and false VDJ recombination: Molecular RT dissection of t(8;14)/MYC-IGH translocations in Burkitt-type lymphoblastic RT leukemia/B-cell lymphoma."; RL Mol. Oncol. 7:850-858(2013). CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AM287168; CAL18347.1; -; Genomic_DNA. DR AlphaFoldDB; B3CJB2; -. DR PeptideAtlas; B3CJB2; -. DR ChiTaRS; MYC; human. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter. DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter. DR GO; GO:0008284; P:positive regulation of cell population proliferation; IEA:TreeGrafter. DR InterPro; IPR050433; Myc_transcription_factors. DR InterPro; IPR002418; Tscrpt_reg_Myc. DR InterPro; IPR012682; Tscrpt_reg_Myc_N. DR PANTHER; PTHR45851; MYC PROTO-ONCOGENE; 1. DR PANTHER; PTHR45851:SF1; MYC PROTO-ONCOGENE PROTEIN; 1. DR Pfam; PF01056; Myc_N; 1. DR PRINTS; PR00044; LEUZIPPRMYC. PE 4: Predicted; FT DOMAIN 2..245 FT /note="Transcription regulator Myc N-terminal" FT /evidence="ECO:0000259|Pfam:PF01056" FT REGION 201..252 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 201..234 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 252 FT /evidence="ECO:0000313|EMBL:CAL18347.1" SQ SEQUENCE 252 AA; 27250 MW; D5CC7090A9B1CEA6 CRC64; MPLNVSFTNR NYDLDYDSVQ PYFYCDEEEN FYQQQQQSEL QPPAPSEDIW KKFELLPTPP LSPSRRSGLC SPSYVAVTPF SLRGDNDGGG GSFSTADQLE MVTELLGGDM VNQSFICDPD DETFIKNIII QDCMWSGFSA AAKLVSEKVA SYQAARKDSG SPNPARGHSV CSTSSLYLQD LSAAASECID PSVVFPYPLN DSSSPKSCAS QDSSAFSPSS DSLLSSTESS PQGSPEPLVL HEETPPTTSS DS //