ID B2RCY5_HUMAN Unreviewed; 633 AA. AC B2RCY5; DT 01-JUL-2008, integrated into UniProtKB/TrEMBL. DT 01-JUL-2008, sequence version 1. DT 31-JUL-2019, entry version 56. DE SubName: Full=cDNA, FLJ96373, highly similar to Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 1 (XRCC1), mRNA {ECO:0000313|EMBL:BAG37732.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG37732.1}; RN [1] {ECO:0000313|EMBL:BAG37732.1} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Placenta {ECO:0000313|EMBL:BAG37732.1}; RA Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., RA Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., RA Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., RA Isogai T.; RT "NEDO functional analysis of protein and research application RT project."; RL Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK315332; BAG37732.1; -; mRNA. DR RefSeq; NP_006288.2; NM_006297.2. DR PeptideAtlas; B2RCY5; -. DR PRIDE; B2RCY5; -. DR GeneID; 7515; -. DR KEGG; hsa:7515; -. DR CTD; 7515; -. DR PharmGKB; PA369; -. DR eggNOG; KOG3226; Eukaryota. DR eggNOG; ENOG410ZE1H; LUCA. DR KO; K10803; -. DR OrthoDB; 539462at2759; -. DR SignaLink; B2RCY5; -. DR GenomeRNAi; 7515; -. DR Genevisible; B2RCY5; HS. DR GO; GO:0005634; C:nucleus; IEA:InterPro. DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro. DR GO; GO:0000012; P:single strand break repair; IEA:InterPro. DR Gene3D; 2.60.120.260; -; 1. DR Gene3D; 3.40.50.10190; -; 2. DR InterPro; IPR001357; BRCT_dom. DR InterPro; IPR036420; BRCT_dom_sf. DR InterPro; IPR008979; Galactose-bd-like_sf. DR InterPro; IPR002706; Xrcc1_N. DR Pfam; PF00533; BRCT; 1. DR Pfam; PF16589; BRCT_2; 1. DR Pfam; PF01834; XRCC1_N; 1. DR SMART; SM00292; BRCT; 2. DR SUPFAM; SSF49785; SSF49785; 1. DR SUPFAM; SSF52113; SSF52113; 2. DR PROSITE; PS50172; BRCT; 2. PE 2: Evidence at transcript level; FT DOMAIN 315 403 BRCT. {ECO:0000259|PROSITE:PS50172}. FT DOMAIN 538 629 BRCT. {ECO:0000259|PROSITE:PS50172}. FT REGION 221 314 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 400 462 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 471 490 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 498 536 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 221 239 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 240 256 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 263 283 Pro-rich. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 428 444 Polar. {ECO:0000256|SAM:MobiDB-lite}. SQ SEQUENCE 633 AA; 69537 MW; 123BEA5277A3ACF0 CRC64; MPEIRLRHVV SCSSQDSTHC AENLLKADTY RKWRAAKAGE KTISVVLQLE KEEQIHSVDI GNDGSAFVEV LVGSSAGGAG EQDYEVLLVT SSFMSPSESR SGSNPNRVRM FGPDKLVRAA AEKRWDRVKI VCSQPYSKDS PFGLSFVRFH SPPDKDEAEA PSQKVTVTKL GQFRVKEEDE SANSLRPGAL FFSRINKTSP VTASDPAGPS YAAATLQASS AASSASPVSR AIGSTSKPQE SPKGKRKLDL NQEEKKTPSK PPAQLSPSVP KRPKLPAPTH TPATAPVPAR AQGAVTGKPR GEGTEPRRPR AGPEELGKIL QGVVVVLSGF QNPFRSELRD KALELGAKYR PDWTRDSTHL ICAFANTPKY SQVLGLGSRI VRKEWVLDCH RMRRRLPSRR YLMAGPGSSS EEDEASHSGG SGDEAPKLPQ KQPQTKTKPT QAAGPSSPQK PPTPEETKAA SPVLQEDIDI EGVQSEGQDN GAEDSGDTED ELRRVAEQKE HRLPPGQEEN GEDPYAGSTD ENTDSEEHQE PPDLPVPELP DFFQGKHFFL YGEFPGDERR KLIRYVTAFN GELEDYMSDR VQFVITAQEW DPSFEEALMD NPSLAFVRPR WIYSCNEKQK LLPHQLYGVV PQA //