ID   NUOC_BURP8              Reviewed;         200 AA.
AC   B2JDM6;
DT   16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 1.
DT   29-OCT-2014, entry version 38.
DE   RecName: Full=NADH-quinone oxidoreductase subunit C {ECO:0000255|HAMAP-Rule:MF_01357};
DE            EC=1.6.99.5 {ECO:0000255|HAMAP-Rule:MF_01357};
DE   AltName: Full=NADH dehydrogenase I subunit C {ECO:0000255|HAMAP-Rule:MF_01357};
DE   AltName: Full=NDH-1 subunit C {ECO:0000255|HAMAP-Rule:MF_01357};
GN   Name=nuoC {ECO:0000255|HAMAP-Rule:MF_01357};
GN   OrderedLocusNames=Bphy_2007;
OS   Burkholderia phymatum (strain DSM 17167 / STM815).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia.
OX   NCBI_TaxID=391038;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17167 / STM815;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Bruce D.,
RA   Goodwin L., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S.,
RA   Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Mikhailova N., Bacher J., Blanchard J., Cohan F.,
RA   James E., Lawrence J., Lizotte-Waniewski M., Moulin L., Rainey P.,
RA   Riley M., Souza V., Wertz J., Young P.;
RT   "Complete sequence of chromosome 1 of Burkholderia phymatum STM815.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: NDH-1 shuttles electrons from NADH, via FMN and iron-
CC       sulfur (Fe-S) centers, to quinones in the respiratory chain. The
CC       immediate electron acceptor for the enzyme in this species is
CC       believed to be ubiquinone. Couples the redox reaction to proton
CC       translocation (for every two electrons transferred, four hydrogen
CC       ions are translocated across the cytoplasmic membrane), and thus
CC       conserves the redox energy in a proton gradient.
CC       {ECO:0000255|HAMAP-Rule:MF_01357}.
CC   -!- CATALYTIC ACTIVITY: NADH + quinone = NAD(+) + quinol.
CC       {ECO:0000255|HAMAP-Rule:MF_01357}.
CC   -!- SUBUNIT: NDH-1 is composed of 14 different subunits. Subunits
CC       NuoB, C, D, E, F, and G constitute the peripheral sector of the
CC       complex. {ECO:0000255|HAMAP-Rule:MF_01357}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01357}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01357}; Cytoplasmic side {ECO:0000255|HAMAP-
CC       Rule:MF_01357}.
CC   -!- SIMILARITY: Belongs to the complex I 30 kDa subunit family.
CC       {ECO:0000255|HAMAP-Rule:MF_01357}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP001043; ACC71186.1; -; Genomic_DNA.
DR   RefSeq; YP_001858232.1; NC_010622.1.
DR   ProteinModelPortal; B2JDM6; -.
DR   STRING; 391038.Bphy_2007; -.
DR   EnsemblBacteria; ACC71186; ACC71186; Bphy_2007.
DR   GeneID; 6243496; -.
DR   KEGG; bph:Bphy_2007; -.
DR   PATRIC; 19190453; VBIBurPhy25146_2139.
DR   eggNOG; COG0852; -.
DR   HOGENOM; HOG000009799; -.
DR   KO; K00332; -.
DR   OMA; HNDLRRI; -.
DR   OrthoDB; EOG60PHFK; -.
DR   BioCyc; BPHY391038:GI4Z-2056-MONOMER; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-HAMAP.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR   GO; GO:0048038; F:quinone binding; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   HAMAP; MF_01357; NDH1_NuoC; 1.
DR   InterPro; IPR010218; NADH_DH_suC.
DR   InterPro; IPR001268; NADH_UbQ_OxRdtase_30kDa_su.
DR   InterPro; IPR020396; NADH_UbQ_OxRdtase_CS.
DR   Pfam; PF00329; Complex1_30kDa; 1.
DR   ProDom; PD001581; NADH_UbQ_OxRdtase_30kDa_su; 1.
DR   TIGRFAMs; TIGR01961; NuoC_fam; 1.
DR   PROSITE; PS00542; COMPLEX1_30K; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Complete proteome; Membrane; NAD;
KW   Oxidoreductase; Quinone; Reference proteome; Transport; Ubiquinone.
FT   CHAIN         1    200       NADH-quinone oxidoreductase subunit C.
FT                                /FTId=PRO_0000358069.
SQ   SEQUENCE   200 AA;  23007 MW;  893749FD387E9CF7 CRC64;
     MASKLETLKA NLEAAFGGRL TSITESIGEL TIVVKADDFL EVATRLRDDA KLHFEQLIDL
     CGIDYQTYGE GAYDGPRFAA VLHLLSITNN WRLRVRVFAP DDDVPLIPSV VEIWNSANWY
     EREAFDLYGI VFEGHPDLRR ILTDYGFIGH PFRKDFPVSG YVEMRYDPEE KRVVYQPVTI
     EPREITPRVI REDRYGGLKH
//