ID B2DF58_9HIV1 Unreviewed; 193 AA. AC B2DF58; DT 10-JUN-2008, integrated into UniProtKB/TrEMBL. DT 10-JUN-2008, sequence version 1. DT 11-MAY-2016, entry version 28. DE RecName: Full=Virion infectivity factor {ECO:0000256|RuleBase:RU003341}; GN Name=vif {ECO:0000313|EMBL:BAG31098.1}; OS Human immunodeficiency virus 1. OC Viruses; Retro-transcribing viruses; Retroviridae; Orthoretrovirinae; OC Lentivirus; Primate lentivirus group. OX NCBI_TaxID=11676 {ECO:0000313|EMBL:BAG31098.1}; OH NCBI_TaxID=9606; Homo sapiens (Human). RN [1] {ECO:0000313|EMBL:BAG31098.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=#398 {ECO:0000313|EMBL:BAG31098.1}; RX PubMed=18620491; DOI=10.1089/aid.2008.0090; RA Ibe S., Shigemi U., Sawaki K., Fujisaki S., Hattori J., Yokomaku Y., RA Mamiya N., Hamaguchi M., Kaneda T.; RT "Analysis of near full-length genomic sequences of drug-resistant HIV- RT 1 spreading among therapy-naive individuals in Nagoya, Japan: amino RT acid mutations associated with viral replication activity."; RL AIDS Res. Hum. Retroviruses 24:1121-1125(2008). CC -!- SUBCELLULAR LOCATION: Host cell membrane CC {ECO:0000256|SAAS:SAAS00594051}; Peripheral membrane protein CC {ECO:0000256|SAAS:SAAS00594051}; Cytoplasmic side CC {ECO:0000256|SAAS:SAAS00594051}. CC -!- SUBCELLULAR LOCATION: Host cytoplasm CC {ECO:0000256|SAAS:SAAS00594053}. CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000256|SAAS:SAAS00594062}. CC -!- SIMILARITY: Belongs to the primate lentivirus group Vif protein CC family. {ECO:0000256|SAAS:SAAS00594061}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB428560; BAG31098.1; -; Genomic_RNA. DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-KW. DR GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-KW. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW. DR GO; GO:0019012; C:virion; IEA:UniProtKB-KW. DR GO; GO:0019058; P:viral life cycle; IEA:InterPro. DR InterPro; IPR000475; Viral_infect. DR Pfam; PF00559; Vif; 1. DR PRINTS; PR00349; VIRIONINFFCT. PE 3: Inferred from homology; KW Host cell membrane {ECO:0000256|SAAS:SAAS00487320}; KW Host cytoplasm {ECO:0000256|SAAS:SAAS00487388}; KW Host membrane {ECO:0000256|SAAS:SAAS00487340}; KW Host-virus interaction {ECO:0000256|SAAS:SAAS00487339}; KW Membrane {ECO:0000256|SAAS:SAAS00487371}; KW Ubl conjugation pathway {ECO:0000256|SAAS:SAAS00487332}; KW Virion {ECO:0000256|SAAS:SAAS00487311}. SQ SEQUENCE 193 AA; 22739 MW; 1D98B76B9DC8A93D CRC64; MENRWQVMIV WQVDRMRINI WKSLVKHHIH ISRKAKRWMY KHHYESTNPR ISSEVHIPLG EAELVITTYW GLHTGERDWQ LGHGVSIEWR KQRYNTQVDP DLADQLIHLY YFDCFSXSAI RNALLGHRVS PRCEYQAGHR KVGSLQYLAL TALITPTKKR KPPLPSVAKL TEDRWNKPQK TKGHRGSHTV NGH //