ID   B1YU47_BURA4            Unreviewed;       259 AA.
AC   B1YU47;
DT   20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT   20-MAY-2008, sequence version 1.
DT   24-JUL-2024, entry version 79.
DE   SubName: Full=Short-chain dehydrogenase/reductase SDR {ECO:0000313|EMBL:ACB64687.1};
GN   OrderedLocusNames=BamMC406_2208 {ECO:0000313|EMBL:ACB64687.1};
OS   Burkholderia ambifaria (strain MC40-6).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=398577 {ECO:0000313|EMBL:ACB64687.1, ECO:0000313|Proteomes:UP000001680};
RN   [1] {ECO:0000313|Proteomes:UP000001680}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MC40-6 {ECO:0000313|Proteomes:UP000001680};
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Ramette A.,
RA   Konstantinidis K., Tiedje J., Richardson P.;
RT   "Complete sequence of chromosome 1 of Burkholderia ambifaria MC40-6.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0007829|PDB:5VPS}
RP   X-RAY CRYSTALLOGRAPHY (1.45 ANGSTROMS).
RX   PubMed=32841567; DOI=10.1021/acs.biochem.0c00490;
RA   Patel S.M., Smith T.G., Morton M., Stiers K.M., Seravalli J., Mayclin S.J.,
RA   Edwards T.E., Tanner J.J., Becker D.F.;
RT   "Cautionary Tale of Using Tris(alkyl)phosphine Reducing Agents with
RT   NAD<sup>+</sup>-Dependent Enzymes.";
RL   Biochemistry 59:3285-3289(2020).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000256|ARBA:ARBA00006484}.
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DR   EMBL; CP001025; ACB64687.1; -; Genomic_DNA.
DR   RefSeq; WP_011657516.1; NC_010551.1.
DR   PDB; 5VPS; X-ray; 1.45 A; A=1-259.
DR   PDBsum; 5VPS; -.
DR   AlphaFoldDB; B1YU47; -.
DR   SMR; B1YU47; -.
DR   GeneID; 69543480; -.
DR   KEGG; bac:BamMC406_2208; -.
DR   HOGENOM; CLU_010194_1_2_4; -.
DR   OrthoDB; 9804774at2; -.
DR   Proteomes; UP000001680; Chromosome 1.
DR   CDD; cd05344; BKR_like_SDR_like; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR050259; SDR.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR42879; 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE; 1.
DR   PANTHER; PTHR42879:SF6; NADPH-DEPENDENT REDUCTASE BACG; 1.
DR   Pfam; PF13561; adh_short_C2; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:5VPS}.
SQ   SEQUENCE   259 AA;  26587 MW;  0CB231EF2A0F7748 CRC64;
     MDLGIAGKTA LVCAASKGLG RGCAEALAAE GVNLVIVART RDTLEETAEE IRAASNVSVT
     AVACDITTPD GRAAALAACP QPDILVNNAG GPPPGDFRDF SHDDWIRALE ANMLTPIELI
     RATVDGMIGR GFGRIVNITS SAVKAPIDVL ALSNGARSGL TGFVAGLSRK VAGQGVTINN
     LLPGLFDTDR IATTLAASAK AQGVTVDELR ARRAKEIPAG RLGTRAEFGA ACAFLCSVHA
     GYITGQNWLL DGGAYPGTF
//