ID GLPK_BURCC Reviewed; 500 AA. AC B1JY43; DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot. DT 29-APR-2008, sequence version 1. DT 16-MAY-2012, entry version 30. DE RecName: Full=Glycerol kinase; DE EC=2.7.1.30; DE AltName: Full=ATP:glycerol 3-phosphotransferase; DE AltName: Full=Glycerokinase; DE Short=GK; GN Name=glpK; OrderedLocusNames=Bcenmc03_2707; OS Burkholderia cenocepacia (strain MC0-3). OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex. OX NCBI_TaxID=406425; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=MC0-3; RA Copeland A., Lucas S., Lapidus A., Barry K., Bruce D., Goodwin L., RA Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., RA Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., RA Hauser L., Kyrpides N., Mikhailova N., Tiedje J., Richardson P.; RT "Complete sequence of chromosome 1 of Burkholderia cenocepacia MC0- RT 3."; RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Key enzyme in the regulation of glycerol uptake and CC metabolism (By similarity). CC -!- CATALYTIC ACTIVITY: ATP + glycerol = ADP + sn-glycerol 3- CC phosphate. CC -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol CC kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1. CC -!- SIMILARITY: Belongs to the FGGY kinase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000958; ACA91867.1; -; Genomic_DNA. DR RefSeq; YP_001765989.1; NC_010508.1. DR ProteinModelPortal; B1JY43; -. DR SMR; B1JY43; 2-497. DR STRING; B1JY43; -. DR GeneID; 6124370; -. DR GenomeReviews; CP000958_GR; Bcenmc03_2707. DR KEGG; bcm:Bcenmc03_2707; -. DR PATRIC; 19092650; VBIBurCen61509_2807. DR eggNOG; COG0554; -. DR HOGENOM; HOG000222134; -. DR KO; K00864; -. DR OMA; ALYGQLC; -. DR ProtClustDB; PRK00047; -. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0004370; F:glycerol kinase activity; IEA:EC. DR GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:InterPro. DR HAMAP; MF_00186; Glycerol_kin; 1; -. DR InterPro; IPR000577; Carb_kinase_FGGY. DR InterPro; IPR018485; Carb_kinase_FGGY_C. DR InterPro; IPR018483; Carb_kinase_FGGY_CS. DR InterPro; IPR018484; Carb_kinase_FGGY_N. DR InterPro; IPR005999; Glycerol_kin. DR PANTHER; PTHR10196; FGGY_kin; 1. DR PANTHER; PTHR10196:SF9; Glycerol_kin; 1. DR Pfam; PF02782; FGGY_C; 1. DR Pfam; PF00370; FGGY_N; 1. DR TIGRFAMs; TIGR01311; Glycerol_kin; 1. DR PROSITE; PS00933; FGGY_KINASES_1; 1. DR PROSITE; PS00445; FGGY_KINASES_2; 1. PE 3: Inferred from homology; KW ATP-binding; Complete proteome; Glycerol metabolism; Kinase; KW Nucleotide-binding; Transferase. FT CHAIN 1 500 Glycerol kinase. FT /FTId=PRO_1000098720. FT NP_BIND 410 414 ATP (By similarity). FT BINDING 13 13 Substrate (By similarity). FT BINDING 17 17 ATP (By similarity). FT BINDING 83 83 Substrate (By similarity). FT BINDING 135 135 Substrate (By similarity). FT BINDING 244 244 Substrate (By similarity). FT BINDING 266 266 ATP (By similarity). FT BINDING 309 309 ATP; via carbonyl oxygen (By similarity). SQ SEQUENCE 500 AA; 54661 MW; 93324BE747D97438 CRC64; MQDQYILALD QGTTSSRAML FDRQGNIVSI AQKEFEQIYP QPGWVEHDPQ EIWSTQAGVA AEAVTRTGLN GTSIAAIGIT NQRETTIVWD RETGQPVYNA IVWQDRRTAD FCDSLKKQGL EAKVRAKTGL PIDSYFSATK IRWILDNVPG ARDKARQGKL AFGTVDSWLV WNFTKHELHV TDVTNASRTM LFNIHTREWD SELLELLDIP RSMLPEVKAS SEIYGHTKTT VFASKIPLAG IAGDQHAALF GQMCTTSGMV KNTYGTGCFL MMNTGDKPIE SKNNLVTTIA WQIGDDVQYA LEGSIFIAGA VVQWLRDGVG LIKTAAEIEA LAASVPHTDG VYLVPAFAGL GAPHWNARAR GSVFGVTRGT SAAHLARAAL DAIAYQSLDV LAAMEADSGI SIGELRVDGG ASANDLLMQF QADLLGVDAV RPQITETTAL GAAYLAGLAI GYWKNLDEVR DQWQLDRRFA PSMPKEQVEQ RMAGWQRAVR AAKAWADDTQ //