ID B1AYC9_MOUSE Unreviewed; 670 AA. AC B1AYC9; DT 08-APR-2008, integrated into UniProtKB/TrEMBL. DT 08-APR-2008, sequence version 1. DT 18-JAN-2017, entry version 77. DE SubName: Full=Amyloid beta (A4) protein-binding, family B, member 1 interacting protein {ECO:0000313|EMBL:CAM24322.1}; DE SubName: Full=Amyloid beta (A4) protein-binding, family B, member 1 interacting protein, isoform CRA_a {ECO:0000313|EMBL:EDL08139.1}; GN Name=Apbb1ip {ECO:0000313|EMBL:CAM24322.1, GN ECO:0000313|MGI:MGI:1861354}; GN ORFNames=mCG_15166 {ECO:0000313|EMBL:EDL08139.1}, RP23-114M13.3-001 GN {ECO:0000313|EMBL:CAM24322.1}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090; RN [1] {ECO:0000313|EMBL:EDL08139.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Mixed {ECO:0000313|EMBL:EDL08139.1}; RX PubMed=12040188; DOI=10.1126/science.1069193; RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., RA Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., RA Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W., RA Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., RA Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., RA Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., RA Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., RA Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., RA Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., RA Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., RA Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., RA Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., RA Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., RA Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., RA Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., RA Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., RA Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., RA Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., RA Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., RA Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., RA Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., RA Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., RA Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., RA Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., RA Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., RA Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., RA Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., RA Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., RA Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., RA Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., RA Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., RA Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.; RT "A comparison of whole-genome shotgun-derived mouse chromosome 16 and RT the human genome."; RL Science 296:1661-1671(2002). RN [2] {ECO:0000313|EMBL:EDL08139.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Mixed {ECO:0000313|EMBL:EDL08139.1}; RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.; RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|EMBL:CAM24322.1} RP NUCLEOTIDE SEQUENCE. RA Matthews N.; RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases. RN [4] {ECO:0000213|PubMed:19144319} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=19144319; DOI=10.1016/j.immuni.2008.11.006; RA Trost M., English L., Lemieux S., Courcelles M., Desjardins M., RA Thibault P.; RT "The phagosomal proteome in interferon-gamma-activated macrophages."; RL Immunity 30:143-154(2009). RN [5] {ECO:0000213|PubMed:21183079} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and RT expression."; RL Cell 143:1174-1189(2010). CC -!- SIMILARITY: Contains 1 PH domain. {ECO:0000256|RuleBase:RU003350}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL845427; CAM24322.1; -; Genomic_DNA. DR EMBL; BX649461; CAM24322.1; JOINED; Genomic_DNA. DR EMBL; CH466542; EDL08139.1; -; Genomic_DNA. DR RefSeq; NP_062329.2; NM_019456.2. DR RefSeq; XP_006498249.1; XM_006498186.2. DR RefSeq; XP_011237441.1; XM_011239139.2. DR UniGene; Mm.14255; -. DR SMR; B1AYC9; -. DR STRING; 10090.ENSMUSP00000014290; -. DR GeneID; 54519; -. DR KEGG; mmu:54519; -. DR CTD; 54518; -. DR MGI; MGI:1861354; Apbb1ip. DR eggNOG; KOG3751; Eukaryota. DR eggNOG; ENOG410XXC8; LUCA. DR HOVERGEN; HBG080806; -. DR KO; K17704; -. DR OMA; KVKYKAP; -. DR OrthoDB; EOG091G05PM; -. DR PhylomeDB; B1AYC9; -. DR ChiTaRS; Apbb1ip; mouse. DR Bgee; ENSMUSG00000026786; -. DR ExpressionAtlas; B1AYC9; baseline and differential. DR GO; GO:0005829; C:cytosol; IEA:Ensembl. DR GO; GO:0042101; C:T cell receptor complex; IEA:Ensembl. DR GO; GO:0045785; P:positive regulation of cell adhesion; IEA:Ensembl. DR GO; GO:0007165; P:signal transduction; IEA:InterPro. DR GO; GO:0002291; P:T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; IEA:Ensembl. DR Gene3D; 2.30.29.30; -; 1. DR InterPro; IPR011993; PH_dom-like. DR InterPro; IPR001849; PH_domain. DR InterPro; IPR000159; RA_dom. DR InterPro; IPR029071; Ubiquitin-rel_dom. DR Pfam; PF00169; PH; 1. DR Pfam; PF00788; RA; 1. DR SMART; SM00233; PH; 1. DR SMART; SM00314; RA; 1. DR SUPFAM; SSF50729; SSF50729; 1. DR SUPFAM; SSF54236; SSF54236; 1. DR PROSITE; PS50003; PH_DOMAIN; 1. DR PROSITE; PS50200; RA; 1. PE 1: Evidence at protein level; KW Coiled coil {ECO:0000256|SAM:Coils}. FT DOMAIN 179 266 Ras-associating. {ECO:0000259|PROSITE: FT PS50200}. FT DOMAIN 313 422 PH. {ECO:0000259|PROSITE:PS50003}. FT COILED 152 176 {ECO:0000256|SAM:Coils}. SQ SEQUENCE 670 AA; 74319 MW; 39EB28E468C479C8 CRC64; MGESNEDIDQ MFSTLLGEMD LLTQSLGVDT LPPPDPNPPR EEFNYTVGFK DLNESLNALE DQDLDALMAD LVADISEAEQ RTIQAQKESS QNQDRFALLR ASDGQGTASG GYGASAAAID VSHHEEALPP PPVEPMLDLL PPPPPPPPPE LLSKEEEEAK AKADKIKLAL EKLKEAKVKK LVVKVHMDDS STKSLMVDER QLARDVLDNL FEKTHCDCNV DWCLYEIYPE LQIERVFEDH ENVVEVLSDW TRDTENKVLF LEKEERYAVF KNPQNFYLDN KGKKENKETN EKMNAKNKEY LLEESFCGTS IIVPELEGAL YLKEDGKKSW KRRYFLLRAS GIYYVPKGKT KTSRDLACFI QFENVNIYYG IQCKMKYKAP TDHCFVLKHP QIQKESQYIK YLCCDDARTL SQWVMGIRIA KYGKTLYDNY QRAVARAGLA SRWTNLGTVG TPMPAQPSTV SSGLKTGTSQ PNGQMPQAIP SAGPPLQEAQ TQIETTKDEK QGLGNHSPGA TRENHRPKSS LPPPPPPVRR SSDTCGSPAL PSKVKGPGTC TFPHPPENFL PPPPPPPPEE DNSGLLPPPP PPPYLEEPPD FVPPPPPPAA VEDSALPPPP PPPPCLSQEI TKSSPLPPKK PLVPPKRQEN QGLPGAPGNS EQDFMSDLMK ALQKKRGNIP //