ID B1ASC8_MOUSE Unreviewed; 173 AA. AC B1ASC8; DT 08-APR-2008, integrated into UniProtKB/TrEMBL. DT 18-SEP-2013, sequence version 2. DT 07-APR-2021, entry version 75. DE RecName: Full=Chromatin modification-related protein MEAF6 {ECO:0000256|ARBA:ARBA00019141}; DE AltName: Full=Esa1-associated factor 6 homolog {ECO:0000256|ARBA:ARBA00015152}; DE Flags: Fragment; GN Name=Meaf6 {ECO:0000313|Ensembl:ENSMUSP00000101777, GN ECO:0000313|MGI:MGI:1917338}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000101777, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000101777, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000101777, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0007829|PubMed:21183079} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and expression."; RL Cell 143:1174-1189(2010). RN [3] {ECO:0007829|PubMed:23806337} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=23806337; DOI=10.1016/j.molcel.2013.06.001; RA Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., RA Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.; RT "SIRT5-mediated lysine desuccinylation impacts diverse metabolic RT pathways."; RL Mol. Cell 50:919-930(2013). RN [4] {ECO:0000313|Ensembl:ENSMUSP00000101777} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000101777}; RG Ensembl; RL Submitted (JUL-2013) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore CC {ECO:0000256|ARBA:ARBA00004629}. CC -!- SIMILARITY: Belongs to the EAF6 family. CC {ECO:0000256|ARBA:ARBA00010916}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL626775; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR MaxQB; B1ASC8; -. DR PeptideAtlas; B1ASC8; -. DR PRIDE; B1ASC8; -. DR ProteomicsDB; 307876; -. DR Antibodypedia; 31724; 111 antibodies. DR Ensembl; ENSMUST00000106171; ENSMUSP00000101777; ENSMUSG00000028863. DR MGI; MGI:1917338; Meaf6. DR GeneTree; ENSGT00390000015257; -. DR HOGENOM; CLU_092163_1_0_1; -. DR ChiTaRS; Meaf6; mouse. DR Proteomes; UP000000589; Chromosome 4. DR Bgee; ENSMUSG00000028863; Expressed in superior cervical ganglion and 253 other tissues. DR ExpressionAtlas; B1ASC8; baseline and differential. DR GO; GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell. DR GO; GO:0000123; C:histone acetyltransferase complex; IEA:InterPro. DR GO; GO:0016573; P:histone acetylation; IEA:InterPro. DR InterPro; IPR015418; Eaf6. DR PANTHER; PTHR13476; PTHR13476; 1. DR Pfam; PF09340; NuA4; 1. PE 1: Evidence at protein level; KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853}; KW Coiled coil {ECO:0000256|ARBA:ARBA00023054}; KW Nucleus {ECO:0000256|ARBA:ARBA00023242}; KW Proteomics identification {ECO:0007829|EPD:B1ASC8, KW ECO:0007829|MaxQB:B1ASC8}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Transcription {ECO:0000256|ARBA:ARBA00023163}; KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}. FT REGION 76..173 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 149..173 FT /note="Polyampholyte" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 1 FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000101777" SQ SEQUENCE 173 AA; 19498 MW; 55163F993B0CB39E CRC64; LAETLANLER QIYAFEGSYL EDTQMYGNII RGWDRYLTNQ KNSNSKNDRR NRKFKEAERL FSKSSVTSAA AVSALAGVQD QLIEKREPGS GTESDTSPDF HNQENEPAQE DPEDLDGSVQ GVKPQKAASS TSSGSHHSSH KKRKNKNRHS PSGMFDYDFE IDLKLNKKPR ADY //