ID B1APE2_HUMAN Unreviewed; 231 AA. AC B1APE2; DT 08-APR-2008, integrated into UniProtKB/TrEMBL. DT 08-APR-2008, sequence version 1. DT 05-SEP-2012, entry version 37. DE SubName: Full=General transcription factor IIB; DE SubName: Full=Transcription initiation factor IIB; DE Flags: Fragment; GN Name=GTF2B; ORFNames=RP11-82K18.1-002; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=16710414; DOI=10.1038/nature04727; RA Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., RA Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C., RA Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., RA McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C., RA Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., RA Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K., RA Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., RA Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., RA Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., RA Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., RA Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., RA Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., RA Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J., RA Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., RA Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S., RA Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., RA James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., RA Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., RA Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., RA Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., RA Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J., RA Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., RA Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., RA Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., RA Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., RA Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., RA Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., RA Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., RA Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R., RA Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., RA Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R., RA Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P., RA Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D., RA Porter K.M., Prigmore E.; RT "The DNA sequence and biological annotation of human chromosome 1."; RL Nature 441:315-321(2006). RN [2] RP NUCLEOTIDE SEQUENCE. RA Wallis J.; RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases. RN [3] RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL445991; CAI41343.1; -; Genomic_DNA. DR IPI; IPI00643006; -. DR UniGene; Hs.481852; -. DR ProteinModelPortal; B1APE2; -. DR SMR; B1APE2; 2-231. DR STRING; B1APE2; -. DR PRIDE; B1APE2; -. DR Ensembl; ENST00000418217; ENSP00000402345; ENSG00000137947. DR HGNC; HGNC:4648; GTF2B. DR GeneTree; ENSGT00390000006671; -. DR HOGENOM; HOG000108634; -. DR HOVERGEN; HBG017914; -. DR Bgee; B1APE2; -. DR GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. DR GO; GO:0006352; P:transcription initiation, DNA-dependent; IEA:InterPro. DR Gene3D; G3DSA:1.10.472.10; Cyclin_related; 1. DR InterPro; IPR013763; Cyclin-like. DR InterPro; IPR000812; TFIIB. DR InterPro; IPR023486; TFIIB_CS. DR InterPro; IPR013150; TFIIB_cyclin. DR InterPro; IPR013137; Znf_TFIIB. DR PANTHER; PTHR11618; TFIIB_euk_relate; 1. DR Pfam; PF08271; TF_Zn_Ribbon; 1. DR Pfam; PF00382; TFIIB; 1. DR PRINTS; PR00685; TIFACTORIIB. DR SMART; SM00385; CYCLIN; 1. DR SUPFAM; SSF47954; Cyclin_like; 1. DR PROSITE; PS00782; TFIIB; 1. DR PROSITE; PS51134; ZF_TFIIB; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 231 231 SQ SEQUENCE 231 AA; 25636 MW; 080BAE8E0C28DD97 CRC64; MASTSRLDAL PRVTCPNHPD AILVEDYRAG DMICPECDRV IDVGSEWRTF SNDKATKDPS RVGDSQNPLL SDGDLSTMIG KGTGAASFDE FGNSKYQNRR TMSSSDRAMM NAFKEITTMA DRINLPRNIV DRTNNLFKQV YEQKSLKGRA NDAIASACLY IACRQEGVPR TFKEICAVSR ISKKEIGRCF KLILKALETS VDLITTGDFM SRFCSNLCLP KQVQMAATHI A //