ID B1AH42_HUMAN Unreviewed; 101 AA. AC B1AH42; DT 08-APR-2008, integrated into UniProtKB/TrEMBL. DT 08-APR-2008, sequence version 1. DT 08-FEB-2011, entry version 16. DE SubName: Full=Axin 1; DE Flags: Fragment; GN Name=AXIN1; ORFNames=LA16c-314G4.3-005; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RA Thomas K.; RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Z69667; CAQ09649.1; -; Genomic_DNA. DR IPI; IPI00889758; -. DR UniGene; Hs.592082; -. DR STRING; B1AH42; -. DR Ensembl; ENST00000421566; ENSP00000405532; ENSG00000103126. DR Ensembl; ENST00000457798; ENSP00000416835; ENSG00000103126. DR HGNC; HGNC:903; AXIN1. DR GeneTree; ENSGT00390000010011; -. DR Bgee; B1AH42; -. DR GO; GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; ISS:RefGenome. DR GO; GO:0005938; C:cell cortex; ISS:RefGenome. DR GO; GO:0016023; C:cytoplasmic membrane-bounded vesicle; ISS:RefGenome. DR GO; GO:0005881; C:cytoplasmic microtubule; ISS:RefGenome. DR GO; GO:0005886; C:plasma membrane; ISS:RefGenome. DR GO; GO:0014069; C:postsynaptic density; ISS:RefGenome. DR GO; GO:0070016; F:armadillo repeat domain binding; ISS:RefGenome. DR GO; GO:0008013; F:beta-catenin binding; ISS:RefGenome. DR GO; GO:0005096; F:GTPase activator activity; ISS:RefGenome. DR GO; GO:0019901; F:protein kinase binding; ISS:RefGenome. DR GO; GO:0004871; F:signal transducer activity; IEA:InterPro. DR GO; GO:0007257; P:activation of JUN kinase activity; ISS:RefGenome. DR GO; GO:0048320; P:axial mesoderm formation; ISS:RefGenome. DR GO; GO:0060823; P:canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation; ISS:RefGenome. DR GO; GO:0008219; P:cell death; ISS:RefGenome. DR GO; GO:0071407; P:cellular response to organic cyclic substance; ISS:RefGenome. DR GO; GO:0031122; P:cytoplasmic microtubule organization; ISS:RefGenome. DR GO; GO:0007368; P:determination of left/right symmetry; ISS:RefGenome. DR GO; GO:0009950; P:dorsal/ventral axis specification; ISS:RefGenome. DR GO; GO:0048048; P:embryonic eye morphogenesis; ISS:RefGenome. DR GO; GO:0060272; P:embryonic skeletal joint morphogenesis; ISS:RefGenome. DR GO; GO:0021797; P:forebrain anterior/posterior pattern formation; ISS:RefGenome. DR GO; GO:0055001; P:muscle cell development; ISS:RefGenome. DR GO; GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:RefGenome. DR GO; GO:0045599; P:negative regulation of fat cell differentiation; ISS:RefGenome. DR GO; GO:0090041; P:negative regulation of gene-specific transcription elongation from RNA polymerase II promoter; ISS:RefGenome. DR GO; GO:0030910; P:olfactory placode formation; ISS:RefGenome. DR GO; GO:0001743; P:optic placode formation; ISS:RefGenome. DR GO; GO:0035412; P:regulation of catenin protein nuclear translocation; ISS:RefGenome. DR GO; GO:0035121; P:tail morphogenesis; ISS:RefGenome. DR GO; GO:0021881; P:Wnt receptor signaling pathway involved in forebrain neuron fate commitment; ISS:RefGenome. DR GO; GO:0090244; P:Wnt receptor signaling pathway involved in somitogenesis; ISS:RefGenome. DR InterPro; IPR001158; DIX. DR Pfam; PF00778; DIX; 1. DR PROSITE; PS50841; DIX; 1. PE 4: Predicted; FT NON_TER 1 1 SQ SEQUENCE 101 AA; 11378 MW; 34AEE46A8FFCFC1C CRC64; LEEEEKRASR APSKQRTRSQ RKVGGGSAQP CDSIVVAYYF CGEPIPYRTL VRGRAVTLGQ FKELLTKKGS YRPPSHLRCC LLTALLTSVL QILLQESERR V //