ID B0ZTA8_BRARO Unreviewed; 251 AA. AC B0ZTA8; DT 08-APR-2008, integrated into UniProtKB/TrEMBL. DT 08-APR-2008, sequence version 1. DT 03-AUG-2022, entry version 46. DE RecName: Full=Chalcone-flavonone isomerase family protein {ECO:0000256|RuleBase:RU361158}; GN Name=CHI1 {ECO:0000313|EMBL:ABY89683.1}; OS Brassica rapa subsp. oleifera (Biennial turnip rape). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica. OX NCBI_TaxID=145471 {ECO:0000313|EMBL:ABY89683.1}; RN [1] {ECO:0000313|EMBL:ABY89683.1} RP NUCLEOTIDE SEQUENCE. RA Xu Z.R., Sun Y., Li C.L., Li Y.H.; RT "Isolation of chalcone-flavanone isomerase (CHI1) from Brassica rapa and RT analysis of its funtion."; RL Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Catalyzes the intramolecular cyclization of bicyclic CC chalcones into tricyclic (S)-flavanones. Responsible for the CC isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) CC into naringenin. {ECO:0000256|ARBA:ARBA00025429}. CC -!- PATHWAY: Secondary metabolite biosynthesis; flavonoid biosynthesis. CC {ECO:0000256|ARBA:ARBA00004966}. CC -!- SIMILARITY: Belongs to the chalcone isomerase family. CC {ECO:0000256|ARBA:ARBA00007166, ECO:0000256|RuleBase:RU361158}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EU402416; ABY89683.1; -; mRNA. DR UniPathway; UPA00154; -. DR GO; GO:0045430; F:chalcone isomerase activity; IEA:UniProtKB-EC. DR GO; GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-UniPathway. DR Gene3D; 1.10.890.20; -; 1. DR Gene3D; 3.50.70.10; -; 2. DR InterPro; IPR044164; CFI. DR InterPro; IPR016087; Chalcone_isomerase. DR InterPro; IPR016088; Chalcone_isomerase_3-sand. DR InterPro; IPR016089; Chalcone_isomerase_bundle_sf. DR InterPro; IPR036298; Chalcone_isomerase_sf. DR PANTHER; PTHR28039; PTHR28039; 1. DR Pfam; PF02431; Chalcone; 1. DR SUPFAM; SSF54626; SSF54626; 1. PE 2: Evidence at transcript level; KW Flavonoid biosynthesis {ECO:0000256|ARBA:ARBA00023241}; KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:ABY89683.1}. FT DOMAIN 18..220 FT /note="Chalcone_isomerase" FT /evidence="ECO:0000259|Pfam:PF02431" FT REGION 224..251 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 224..239 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 251 AA; 27083 MW; 1C17FC23AE1C2AC4 CRC64; MSSSNCPSPL PTVTKLQVDS VTFPPSVISP ASSNPLFLGG AGVRGLDIQG KFVIFTVIGV YLDPVSVTSL SVKWKGKTTE ELTESVPFFR EIVTGSFEKF IKVTMKLPLT GQQYSEKVTE NCVAIWKSLG IYTDSEAKAV ERFMEVFKDE TFPPGASILF ALSPEGSLTV AFSKDDSIPE TGKVVIENKL LAEAVLESII GKNGVSPGAR LSVAERLAQL MNSDKIEEDA TKTDQEEAND LPLGDQLAKE N //