ID B0ZCL0_ARATH Unreviewed; 350 AA. AC B0ZCL0; DT 08-APR-2008, integrated into UniProtKB/TrEMBL. DT 08-APR-2008, sequence version 1. DT 27-NOV-2024, entry version 77. DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483}; DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483}; DE Flags: Fragment; OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis. OX NCBI_TaxID=3702 {ECO:0000313|EMBL:ABZ04797.1}; RN [1] {ECO:0000313|EMBL:ABZ04797.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=18273534; DOI=10.1007/s00239-007-9063-3; RA Moore R.C., Stevens M.H.H.; RT "Local patterns of nucleotide polymorphism are highly variable in the RT selfing species Arabidopsis thaliana."; RL J. Mol. Evol. 66:116-129(2008). CC -!- CATALYTIC ACTIVITY: CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L- CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.; CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900}; CC -!- PATHWAY: Protein modification; protein ubiquitination. CC {ECO:0000256|ARBA:ARBA00004906}. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. CC -!- SIMILARITY: Belongs to the RING-type zinc finger family. ATL subfamily. CC {ECO:0000256|ARBA:ARBA00024209}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EU351853; ABZ04797.1; -; Genomic_DNA. DR AlphaFoldDB; B0ZCL0; -. DR ExpressionAtlas; B0ZCL0; baseline and differential. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW. DR GO; GO:0016740; F:transferase activity; IEA:InterPro. DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro. DR CDD; cd16461; RING-H2_EL5-like; 1. DR FunFam; 3.30.40.10:FF:000187; E3 ubiquitin-protein ligase ATL6; 1. DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1. DR InterPro; IPR044600; ATL1/ATL16-like. DR InterPro; IPR001841; Znf_RING. DR InterPro; IPR013083; Znf_RING/FYVE/PHD. DR PANTHER; PTHR46913:SF16; RING-H2 FINGER PROTEIN ATL1; 1. DR PANTHER; PTHR46913; RING-H2 FINGER PROTEIN ATL16; 1. DR Pfam; PF13639; zf-RING_2; 1. DR SMART; SM00184; RING; 1. DR SUPFAM; SSF57850; RING/U-box; 1. DR PROSITE; PS50089; ZF_RING_2; 1. PE 3: Inferred from homology; KW Membrane {ECO:0000256|SAM:Phobius}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE- KW ProRule:PRU00175}; Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}; KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}; KW Zinc {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-ProRule:PRU00175}; KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE- KW ProRule:PRU00175}. FT TRANSMEM 23..46 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 116..158 FT /note="RING-type" FT /evidence="ECO:0000259|PROSITE:PS50089" FT REGION 231..251 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 316..336 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 231..246 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:ABZ04797.1" FT NON_TER 350 FT /evidence="ECO:0000313|EMBL:ABZ04797.1" SQ SEQUENCE 350 AA; 39089 MW; 9C9D7E31EDEB850E CRC64; PPPPSTTFTS PIFPRTSSSG TNFPILAIAV IGILATAFLL VSYYIFVIKC CLNWHQIDIF RRRRRSSDQN PLMIYSPHEV NRGLDESAIR AIPVFKFKKR DVVAGEEDQS KNSQECSVCL NEFQEDEKLR IIPNCCHVFH IDCIDIWLQG NANCPLCRTS VSCEASFTLD LISAPSSPRE NSPHSRNRNL EPGLVLGGDD DFVVIELGAS NGNNRESVRN IDFLTEQERV TSNEVSTGNS PKSVSPLPIK FGNRGMYKKE RKFHKVTSMG DECIDTRGKD GHFGEIQPIR RSISMDSSVD RQLYLAVQEE ISRRNRQIPV AGDGEDSSSS GGGNSRVMKR CFFSFGSSRT //