ID   B0SKG4_LEPBP            Unreviewed;       313 AA.
AC   B0SKG4;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   27-JUL-2011, entry version 27.
DE   RecName: Full=Ribose-phosphate pyrophosphokinase;
DE            EC=2.7.6.1;
GN   Name=prs; OrderedLocusNames=LEPBI_I0236;
OS   Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 /
OS   Paris).
OC   Bacteria; Spirochaetes; Spirochaetales; Leptospiraceae; Leptospira.
OX   NCBI_TaxID=456481;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=18270594; DOI=10.1371/journal.pone.0001607;
RA   Picardeau M., Bulach D.M., Bouchier C., Zuerner R.L., Zidane N.,
RA   Wilson P.J., Creno S., Kuczek E.S., Bommezzadri S., Davis J.C.,
RA   McGrath A., Johnson M.J., Boursaux-Eude C., Seemann T., Rouy Z.,
RA   Coppel R.L., Rood J.I., Lajus A., Davies J.K., Medigue C., Adler B.;
RT   "Genome sequence of the saprophyte Leptospira biflexa provides
RT   insights into the evolution of Leptospira and the pathogenesis of
RT   leptospirosis.";
RL   PLoS ONE 3:E1607-E1607(2008).
CC   -!- CATALYTIC ACTIVITY: ATP + D-ribose 5-phosphate = AMP + 5-phospho-
CC       alpha-D-ribose 1-diphosphate.
CC   -!- SIMILARITY: Belongs to the ribose-phosphate pyrophosphokinase
CC       family.
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DR   EMBL; CP000786; ABZ96381.1; -; Genomic_DNA.
DR   RefSeq; YP_001837657.1; NC_010602.1.
DR   ProteinModelPortal; B0SKG4; -.
DR   SMR; B0SKG4; 6-313.
DR   STRING; B0SKG4; -.
DR   GeneID; 6222071; -.
DR   GenomeReviews; CP000786_GR; LEPBI_I0236.
DR   KEGG; lbi:LEPBI_I0236; -.
DR   HOGENOM; HBG519284; -.
DR   OMA; CATHAVF; -.
DR   ProtClustDB; PRK01259; -.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
DR   GO; GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
DR   GO; GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_00583_B; RibP_PPkinase_B; 1; -.
DR   InterPro; IPR000842; PRib_PP_synth_CS.
DR   InterPro; IPR000836; PRibTrfase.
DR   InterPro; IPR005946; Rib-P_diPkinase.
DR   Pfam; PF00156; Pribosyltran; 1.
DR   TIGRFAMs; TIGR01251; RibP_PPkin; 1.
DR   PROSITE; PS00114; PRPP_SYNTHASE; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Kinase; Magnesium; Metal-binding;
KW   Nucleotide biosynthesis; Transferase.
SQ   SEQUENCE   313 AA;  34213 MW;  950A2469A64B5321 CRC64;
     MNPSEVVVFS GNANRPLAEE ICKNLKIPNG QISVKRFSDG ESSVKIEENV RGRDVFVVQS
     ISYPANDSLM ELLLIIDAAR RASARRITAV IPYYGYGRQD RKVEPRVPIS ARMVADLIET
     VGPDRVLTMD LHADQIQGFF RIPVDHLYFS PVLAEYINSL GMDDLVIVSP DSGGAERARN
     FGKKVNGSLA IIDKRRPKAN ESVVMHVIGD IKDKNCLLLD DMIDTGGTIA KAATALYENG
     AKSVLCCASH GVLSGEAPSK LNEAKFNPIV LSNSIVIPES KKINHLKTLS IAPLFAKAIE
     RIHNEESISS LFS
//