ID A9YD18_HUMAN Unreviewed; 130 AA. AC A9YD18; DT 05-FEB-2008, integrated into UniProtKB/TrEMBL. DT 05-FEB-2008, sequence version 1. DT 31-JAN-2018, entry version 34. DE SubName: Full=BCR/ABL e8a2 fusion protein {ECO:0000313|EMBL:ABX79391.1}; DE Flags: Fragment; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:ABX79391.1}; RN [1] {ECO:0000313|EMBL:ABX79391.1} RP NUCLEOTIDE SEQUENCE. RA Santamaria I., Pitiot A.S., Payer A.R., Balbin M.; RT "Identification of a rare e8a2 BCR-ABL fusion gene in a chronic RT myeloid leukemia (CML) patient treated with Dasatinib."; RL Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EU154998; ABX79391.1; -; mRNA. DR SMR; A9YD18; -. DR iPTMnet; A9YD18; -. DR PeptideAtlas; A9YD18; -. DR PRIDE; A9YD18; -. DR eggNOG; KOG4269; Eukaryota. DR eggNOG; ENOG410XPGZ; LUCA. DR GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. DR GO; GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. DR Gene3D; 1.20.900.10; -; 1. DR InterPro; IPR035899; DBL_dom_sf. DR InterPro; IPR000219; DH-domain. DR Pfam; PF00621; RhoGEF; 1. DR SUPFAM; SSF48065; SSF48065; 1. DR PROSITE; PS50010; DH_2; 1. PE 2: Evidence at transcript level; FT DOMAIN 1 50 DH. {ECO:0000259|PROSITE:PS50010}. FT NON_TER 1 1 {ECO:0000313|EMBL:ABX79391.1}. FT NON_TER 130 130 {ECO:0000313|EMBL:ABX79391.1}. SQ SEQUENCE 130 AA; 14404 MW; 7E0678B2A6D866F1 CRC64; LLYKPVDRVT RSTLVLHDLL KHTPASHPDH PLLQDALRIS QNFLSSINEE ITPRRQSMTV KKGEAGLELL TSEALQRPVA SDFEPQGLSE AARWNSKENL LAGPSENDPN LFVALYDFVA SGDNTLSITK //