ID A9Y695_9HIV1 Unreviewed; 86 AA. AC A9Y695; DT 05-FEB-2008, integrated into UniProtKB/TrEMBL. DT 05-FEB-2008, sequence version 1. DT 12-SEP-2018, entry version 48. DE RecName: Full=Protein Tat {ECO:0000256|RuleBase:RU003311, ECO:0000256|SAAS:SAAS00396010}; GN Name=tat {ECO:0000313|EMBL:ABW86719.1}; OS Human immunodeficiency virus 1. OC Viruses; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus. OX NCBI_TaxID=11676 {ECO:0000313|EMBL:ABW86719.1, ECO:0000313|Proteomes:UP000102958}; OH NCBI_TaxID=9606; Homo sapiens (Human). RN [1] {ECO:0000313|EMBL:ABW86719.1, ECO:0000313|Proteomes:UP000102958} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ML1974 {ECO:0000313|EMBL:ABW86719.1}; RX PubMed=18544023; DOI=10.1089/aid.2007.0200; RA Land A.M., Ball T.B., Luo M., Rutherford J., Sarna C., Wachihi C., RA Kimani J., Plummer F.A.; RT "Full-length HIV type 1 proviral sequencing of 10 highly exposed women RT from Nairobi, Kenya reveals a high proportion of intersubtype RT recombinants."; RL AIDS Res. Hum. Retroviruses 24:865-872(2008). CC -!- SUBCELLULAR LOCATION: Host nucleus, host nucleolus CC {ECO:0000256|RuleBase:RU003311, ECO:0000256|SAAS:SAAS00581732}. CC -!- SIMILARITY: Belongs to the lentiviruses Tat family. CC {ECO:0000256|RuleBase:RU003311, ECO:0000256|SAAS:SAAS00581731}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EU110090; ABW86719.1; -; Genomic_DNA. DR ProteinModelPortal; A9Y695; -. DR Proteomes; UP000102958; Genome. DR GO; GO:0044196; C:host cell nucleolus; IEA:UniProtKB-SubCell. DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW. DR GO; GO:0001070; F:RNA-binding transcription regulator activity; IEA:InterPro. DR GO; GO:0050434; P:positive regulation of viral transcription; IEA:InterPro. DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW. DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW. DR GO; GO:0016032; P:viral process; IEA:UniProtKB-KW. DR Gene3D; 4.10.20.10; -; 1. DR HAMAP; MF_04079; HIV_TAT; 1. DR InterPro; IPR001831; IV_Tat. DR InterPro; IPR036963; Tat_dom_sf. DR Pfam; PF00539; Tat; 1. DR PRINTS; PR00055; HIVTATDOMAIN. PE 3: Inferred from homology; KW Activator {ECO:0000256|RuleBase:RU003311, KW ECO:0000256|SAAS:SAAS00111091}; KW Complete proteome {ECO:0000313|Proteomes:UP000102958}; KW Host nucleus {ECO:0000256|RuleBase:RU003311, KW ECO:0000256|SAAS:SAAS00473431}; KW Host-virus interaction {ECO:0000256|SAAS:SAAS00111166}; KW RNA-binding {ECO:0000256|RuleBase:RU003311, KW ECO:0000256|SAAS:SAAS00111359}; KW Transcription {ECO:0000256|RuleBase:RU003311, KW ECO:0000256|SAAS:SAAS00111391}; KW Transcription regulation {ECO:0000256|RuleBase:RU003311, KW ECO:0000256|SAAS:SAAS00111074}. SQ SEQUENCE 86 AA; 9837 MW; E739BC496DEAEB73 CRC64; MDPVDPRLEP WNHPGSQPRT PCNQCYCKKC CYHCQHCFIT KGLGISYGRK KRRQRRSAPH GDQSHQDPIP KQPSSQPRGD PTGPKE //