ID   A9UZF4_MONBE            Unreviewed;       450 AA.
AC   A9UZF4;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   25-OCT-2017, entry version 50.
DE   SubName: Full=Predicted protein {ECO:0000313|EMBL:EDQ89358.1};
GN   ORFNames=25438 {ECO:0000313|EMBL:EDQ89358.1};
OS   Monosiga brevicollis (Choanoflagellate).
OC   Eukaryota; Choanoflagellida; Craspedida; Salpingoecidae; Monosiga.
OX   NCBI_TaxID=81824 {ECO:0000313|Proteomes:UP000001357};
RN   [1] {ECO:0000313|EMBL:EDQ89358.1, ECO:0000313|Proteomes:UP000001357}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX   PubMed=18273011; DOI=10.1038/nature06617;
RG   JGI Sequencing;
RA   King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA   Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA   Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA   Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA   Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA   McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT   "The genome of the choanoflagellate Monosiga brevicollis and the
RT   origin of metazoans.";
RL   Nature 451:783-788(2008).
RN   [2] {ECO:0000213|PDB:2RVF}
RP   STRUCTURE BY NMR OF 58-119.
RX   PubMed=27686861; DOI=10.1038/srep34349;
RA   Shigeno-Nakazawa Y., Kasai T., Ki S., Kostyanovskaya E., Pawlak J.,
RA   Yamagishi J., Okimoto N., Taiji M., Okada M., Westbrook J., Satta Y.,
RA   Kigawa T., Imamoto A.;
RT   "A pre-metazoan origin of the CRK gene family and co-opted signaling
RT   network.";
RL   Sci. Rep. 6:34349-34349(2016).
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DR   EMBL; CH991551; EDQ89358.1; -; Genomic_DNA.
DR   RefSeq; XP_001745934.1; XM_001745882.1.
DR   PDB; 2RVF; NMR; -; A=58-119.
DR   PDBsum; 2RVF; -.
DR   ProteinModelPortal; A9UZF4; -.
DR   SMR; A9UZF4; -.
DR   STRING; 431895.XP_001745934.1; -.
DR   EnsemblProtists; EDQ89358; EDQ89358; MONBRDRAFT_25438.
DR   GeneID; 5891245; -.
DR   KEGG; mbr:MONBRDRAFT_25438; -.
DR   eggNOG; KOG4792; Eukaryota.
DR   eggNOG; ENOG4110574; LUCA.
DR   InParanoid; A9UZF4; -.
DR   OMA; YMEHELE; -.
DR   Proteomes; UP000001357; Unassembled WGS sequence.
DR   Gene3D; 3.30.505.10; -; 1.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR036028; SH3-like_dom.
DR   InterPro; IPR001452; SH3_domain.
DR   Pfam; PF00017; SH2; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00326; SH3; 2.
DR   SUPFAM; SSF50044; SSF50044; 1.
DR   SUPFAM; SSF55550; SSF55550; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0000213|PDB:2RVF};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001357};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001357};
KW   SH3 domain {ECO:0000256|PROSITE-ProRule:PRU00192};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    450       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002742596.
FT   DOMAIN      131    192       SH3. {ECO:0000259|PROSITE:PS50002}.
SQ   SEQUENCE   450 AA;  48449 MW;  2D4C0B21E403A235 CRC64;
     MCFFFCLLLS LFLSLCLSVS LCLSVSLSLC LSLSVSLSLC LSVSLSLSLS PSLSLSLTSS
     PGDYVLSCSE NGKVTHYKLS AEEGKIRIDT HLFDNLDAAI TFYMEHELEY SSLKQPLQRQ
     SSWRDDELVA TVMFSAEGLY KFVGRNENDL PFDKGELLNV LQLTQDNWWM AQSQKTLKIG
     YVPVNYVRAL EQPAAPPPRP APRPAEEESS RLERTESRRT PASHHRPKEP MPAGAVMTRA
     PARHHQEAKA PPARPQPTGP SAAGPIAAAA PPPRPKTSKP TTDFSALKAQ LQEPIVSNPT
     PTSTAPEQAA LPAETTAEVS TPTQPLASAP PTSTASHEAP ASSAAPATQH GAGSEDHATA
     PDSEPPITLV RAITAIIPNA YDNDALVLEE NDLVHVLDGG EGALERGRVL RTGQIGLYPF
     AKTEDIESHN YDAEVKAAVA DYLKRFPDAC
//