ID PESC_MONBE Reviewed; 589 AA. AC A9URZ4; DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot. DT 05-FEB-2008, sequence version 1. DT 22-JUL-2015, entry version 37. DE RecName: Full=Pescadillo homolog {ECO:0000255|HAMAP-Rule:MF_03028}; GN ORFNames=19511; OS Monosiga brevicollis (Choanoflagellate). OC Eukaryota; Choanoflagellida; Codonosigidae; Monosiga. OX NCBI_TaxID=81824; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=MX1 / ATCC 50154; RX PubMed=18273011; DOI=10.1038/nature06617; RG JGI Sequencing; RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J., RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D., RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M., RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S., RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T., RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.; RT "The genome of the choanoflagellate Monosiga brevicollis and the RT origin of metazoans."; RL Nature 451:783-788(2008). CC -!- FUNCTION: Required for maturation of ribosomal RNAs and formation CC of the large ribosomal subunit. {ECO:0000255|HAMAP-Rule:MF_03028}. CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000255|HAMAP- CC Rule:MF_03028}. Nucleus, nucleoplasm {ECO:0000255|HAMAP- CC Rule:MF_03028}. CC -!- SIMILARITY: Belongs to the pescadillo family. {ECO:0000255|HAMAP- CC Rule:MF_03028}. CC -!- SIMILARITY: Contains 1 BRCT domain. {ECO:0000255|HAMAP- CC Rule:MF_03028}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CH991544; EDQ92012.1; -; Genomic_DNA. DR RefSeq; XP_001743298.1; XM_001743246.1. DR ProteinModelPortal; A9URZ4; -. DR SMR; A9URZ4; 347-438. DR STRING; 431895.XP_001743298.1; -. DR GeneID; 5888647; -. DR KEGG; mbr:MONBRDRAFT_19511; -. DR eggNOG; COG5163; -. DR InParanoid; A9URZ4; -. DR KO; K14843; -. DR OMA; FKGLKFF; -. DR Proteomes; UP000001357; Unassembled WGS sequence. DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0070545; C:PeBoW complex; IBA:GO_Central. DR GO; GO:0030687; C:preribosome, large subunit precursor; IEA:UniProtKB-HAMAP. DR GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:UniProtKB-HAMAP. DR GO; GO:0003723; F:RNA binding; IBA:GO_Central. DR GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-HAMAP. DR GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central. DR Gene3D; 3.40.50.10190; -; 1. DR HAMAP; MF_03028; Pescadillo; 1. DR InterPro; IPR001357; BRCT_dom. DR InterPro; IPR010613; PES. DR Pfam; PF00533; BRCT; 1. DR Pfam; PF06732; Pescadillo_N; 1. DR SMART; SM00292; BRCT; 1. DR SUPFAM; SSF52113; SSF52113; 1. DR PROSITE; PS50172; BRCT; 1. PE 3: Inferred from homology; KW Coiled coil; Complete proteome; Nucleus; Reference proteome; KW Ribosome biogenesis; rRNA processing. FT CHAIN 1 589 Pescadillo homolog. FT /FTId=PRO_0000370468. FT DOMAIN 346 440 BRCT. {ECO:0000255|HAMAP-Rule:MF_03028}. FT COILED 261 305 {ECO:0000255|HAMAP-Rule:MF_03028}. FT COILED 520 587 {ECO:0000255|HAMAP-Rule:MF_03028}. SQ SEQUENCE 589 AA; 67430 MW; 9136EA2A77251B3E CRC64; MGRIKKKGEE GTATEYMSRS RAVRKLQLSL ADFRRLCILK GIYPREPPNK KKVTGSTANR TYYFVKDINW LLHEPLLQRF RELKTYARRL KKAEAKDQPG VVKAIRRREP KVKVNHLVKE RYPSFVDAIR DLDDCLCMLF LFASFPQTGV IRARMVEKCR RLCNEFMLYV VRARALRKVF LSIKGIYYQA EIMGQTVTWI APYQFATDVP TDVDFRVMGT FLQFYLTLLG FVNFKLYATL GMHYPPQFEA AQSEASETMS KHHRKQAKKT ESRVAQALAD VKAAMDEDLN DEEEELDAQT KQEAAPADRD QASFDTFEAM ADPAVDSDMN VPSGQDLEEA AAEADAATRI FQNLYFFLSR EVPRYSLEFV IRSFGGNVSW DALDEAEAGP YGVDDPRITH HIVDRPAVSQ TFDGRHYVQP QWVYDCINAK ALLPTSTYTL GAVLPPHLSP FVEEGADDYM PPERRAQLAA AKNIHSTDMT IDESEAPEEI DDEDIYRKEL EAELRGDDTA EAPEEPKGNT AKRKKTKAEK GKAAEEERKE MAKLMMSKRD RTLYNRIVHS KKQKQVEAQK LTARRQQIDK EKSAKKSKK //