ID   A9ULS6_DANRE            Unreviewed;       244 AA.
AC   A9ULS6;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   SubName: Full=Zgc:175259 protein {ECO:0000313|EMBL:AAI57382.1};
GN   Name=zgc:175259 {ECO:0000313|EMBL:AAI57382.1};
GN   OrderedLocusNames=aqp8b {ECO:0000313|ZFIN:ZDB-GENE-080220-47};
GN   ORFNames=SO:0001217 {ECO:0000313|ZFIN:ZDB-GENE-080220-47};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|EMBL:AAI57382.1};
RN   [1] {ECO:0000313|EMBL:AAI57382.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo {ECO:0000313|EMBL:AAI57382.1};
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
CC       {ECO:0000256|ARBA:ARBA00006175, ECO:0000256|RuleBase:RU000477}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC157381; AAI57382.1; -; mRNA.
DR   ZFIN; ZDB-GENE-080220-47; aqp8b.
DR   ZFIN; ZDB-GENE-080220-47; SO:0001217.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0015250; F:water channel activity; IBA:GO_Central.
DR   GO; GO:0005372; F:water transmembrane transporter activity; IDA:ZFIN.
DR   GO; GO:0006833; P:water transport; IBA:GO_Central.
DR   Gene3D; 1.20.1080.10; -; 1.
DR   InterPro; IPR023271; Aquaporin-like.
DR   InterPro; IPR023277; Aquaporin_8.
DR   InterPro; IPR034294; Aquaporin_transptr.
DR   InterPro; IPR000425; MIP.
DR   InterPro; IPR022357; MIP_CS.
DR   PANTHER; PTHR45665; PTHR45665; 1.
DR   Pfam; PF00230; MIP; 1.
DR   PRINTS; PR02020; AQUAPORIN8.
DR   PRINTS; PR00783; MINTRINSICP.
DR   SUPFAM; SSF81338; SSF81338; 1.
DR   PROSITE; PS00221; MIP; 1.
PE   2: Evidence at transcript level;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000477};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000477}.
FT   TRANSMEM        19..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        54..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        143..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        213..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   244 AA;  25836 MW;  1CF1E89C7100B42F CRC64;
     MDKMVQETEM EEPGLFEQLV QPCMAELVGT AFFVLMGCLC VIESAQEGHT LQAALVHGLA
     LAVVIGCMVE ISGSHFNPSF TIAVFLSGGL ELKMVLPYLI SQVSGGLLGA VMAKGMTSSE
     KYAQAQGAAF TVLQADDHIM KALFAEAAMT CLATLAVLLS AVNGKSKNHM FPFLVGCTVM
     VNVLAGANVS GACLNPVRAL GPAVLTNYWT HHWIYWVGPI TGGLIAAALV RLFLGDNDTR
     VVMK
//