ID   A9Q7D2_PAPAN            Unreviewed;       234 AA.
AC   A9Q7D2;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   27-NOV-2024, entry version 49.
DE   SubName: Full=Somatostatin receptor 1 {ECO:0000313|EMBL:ABV08868.1};
DE   Flags: Fragment;
OS   Papio anubis (Olive baboon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Papio.
OX   NCBI_TaxID=9555 {ECO:0000313|EMBL:ABV08868.1};
RN   [1] {ECO:0000313|EMBL:ABV08868.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Kineman R.D., Luque R.M.;
RT   "Low doses of somatostatin signal through AC/cAMP to dramatically increase
RT   GH release in primary pituitary cell cultures from a non-human primate
RT   (Papio anubis).";
RL   Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000256|RuleBase:RU000688}.
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DR   EMBL; EF639291; ABV08868.1; -; mRNA.
DR   AlphaFoldDB; A9Q7D2; -.
DR   GO; GO:0043005; C:neuron projection; IEA:TreeGrafter.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0042923; F:neuropeptide binding; IEA:TreeGrafter.
DR   GO; GO:0004994; F:somatostatin receptor activity; IEA:InterPro.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; IEA:TreeGrafter.
DR   GO; GO:0007187; P:G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; IEA:UniProt.
DR   GO; GO:0008285; P:negative regulation of cell population proliferation; IEA:UniProt.
DR   FunFam; 1.20.1070.10:FF:000060; Somatostatin receptor type 1; 1.
DR   Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000586; Somatstn_rcpt.
DR   InterPro; IPR001116; Somatstn_rcpt_1.
DR   PANTHER; PTHR24229; NEUROPEPTIDES RECEPTOR; 1.
DR   PANTHER; PTHR24229:SF38; SOMATOSTATIN RECEPTOR TYPE 1; 1.
DR   Pfam; PF00001; 7tm_1; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00246; SOMATOSTATNR.
DR   PRINTS; PR00587; SOMATOSTTN1R.
DR   SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040,
KW   ECO:0000256|RuleBase:RU000688};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU000688};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU000688};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000688};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        42..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        123..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        173..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        211..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..227
FT                   /note="G-protein coupled receptors family 1 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50262"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ABV08868.1"
FT   NON_TER         234
FT                   /evidence="ECO:0000313|EMBL:ABV08868.1"
SQ   SEQUENCE   234 AA;  26190 MW;  E9B8CAA4346C2C4B CRC64;
     ILNLAIADEL LMLSVPFLVT STLLRHWPFG ALLCRLVLSV DAVNMFTSIY CLTVLSVDRY
     VAVVHPIKAA RYRRPTVAKV VNLGVWVLSL LVILPIVVFS RTAANSDGTV ACNMLMPEPA
     QRWLVGFVLY TFLMGFLLPV GAICLCYVLI IAKMRMVALK AGWQQRKRSE RKITLMVMMV
     VMVFVICWMP FYVVQLVNVF AEQDDATVSQ LSVILGYANS CANPILYGFL SDNF
//