ID THII_SALAR Reviewed; 482 AA. AC A9MM39; DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot. DT 05-FEB-2008, sequence version 1. DT 09-FEB-2010, entry version 19. DE RecName: Full=Thiamine biosynthesis protein thiI; GN Name=thiI; OrderedLocusNames=SARI_02502; OS Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980). OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Salmonella. OX NCBI_TaxID=41514; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., RA Fulton R., Chunyan W., Wollam A., Shah N., Pepin K., Bhonagiri V., RA Nash W., Johnson M., Thiruvilangam P., Wilson R.; RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Required for the synthesis of the thiazole moiety (By CC similarity). CC -!- PATHWAY: Cofactor biosynthesis; thiamine diphosphate biosynthesis. CC -!- SUBCELLULAR LOCATION: Cytoplasm (Potential). CC -!- SIMILARITY: Belongs to the thiI family. CC -!- SIMILARITY: Contains 1 rhodanese domain. CC -!- SIMILARITY: Contains 1 THUMP domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000880; ABX22361.1; -; Genomic_DNA. DR RefSeq; YP_001571503.1; -. DR SMR; A9MM39; 3-387, 178-424. DR GeneID; 5761943; -. DR GenomeReviews; CP000880_GR; SARI_02502. DR KEGG; ses:SARI_02502; -. DR HOGENOM; HBG646072; -. DR OMA; GYPIGTQ; -. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW. DR GO; GO:0009228; P:thiamin biosynthetic process; IEA:HAMAP. DR HAMAP; MF_00021; ThiI; 1; -. DR InterPro; IPR001763; Rhodanese-like. DR InterPro; IPR003720; ThiI. DR InterPro; IPR020536; ThiI_C. DR InterPro; IPR004114; THUMP. DR Pfam; PF02568; ThiI; 1. DR Pfam; PF02926; THUMP; 1. DR TIGRFAMs; TIGR00342; ThiI; 1. DR PROSITE; PS50206; RHODANESE_3; 1. DR PROSITE; PS51165; THUMP; 1. PE 3: Inferred from homology; KW Complete proteome; Cytoplasm; RNA-binding; Thiamine biosynthesis. FT CHAIN 1 482 Thiamine biosynthesis protein thiI. FT /FTId=PRO_1000074257. FT DOMAIN 61 165 THUMP. FT DOMAIN 404 482 Rhodanese. FT ACT_SITE 456 456 Cysteine persulfide intermediate (By FT similarity). SQ SEQUENCE 482 AA; 54745 MW; DD22EE603796F147 CRC64; MKFIIKLFPE ITIKSQSVRL RFIKILAGNI RNVLKHYDET LAVVRHWDNI EVRAKDENQR LAIRDALTRI PGIHHILEVE DVPFTDMHDI FEKALAQYRE QLEGKTFCVR VKRRGKHEFS SIEVERYVGG GLNQHIESAR VKLANPDVTV HLEVEDDRLL LIKGRYEGIG GFPIGTQEDV LSLISGGFDS GVSSYMLMRR GCRVHYCFFN LGGAAHEIGV RQVAHYLWNR FGSSHRVRFV AINFEPVVGE ILEKVDDGQM GVVLKRMMVR AASKVAERYG VQALVTGEAL GQVSSQTLTN LRLIDNVSDT LILRPLISYD KEHIINLARQ IGTEDFARTM PEYCGVISKS PTVKAIKAKI EAEEENFDFS ILDKVVEEAN NVDIREIAQQ TQQEVVEVET VSGFGANDVI LDIRSIDEQD DKPLKVEGID VVSLPFYKLS TKFGDLDQSK TWLLWCERGV MSRLQALYLR EQGFANVKVY RP //