ID A9MHM5_SALAR Unreviewed; 525 AA. AC A9MHM5; DT 05-FEB-2008, integrated into UniProtKB/TrEMBL. DT 05-FEB-2008, sequence version 1. DT 24-MAR-2009, entry version 16. DE SubName: Full=Putative uncharacterized protein; GN OrderedLocusNames=SARI_00366; OS Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980). OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Salmonella. OX NCBI_TaxID=41514; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., RA Fulton R., Chunyan W., Wollam A., Shah N., Pepin K., Bhonagiri V., RA Nash W., Johnson M., Thiruvilangam P., Wilson R.; RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Catalyzes the synthesis of GMP from XMP (By CC Similarity).. CC -!- CATALYTIC ACTIVITY: ATP + xanthosine 5'-phosphate + L-glutamine + CC H(2)O = AMP + diphosphate + GMP + L-glutamate. CC -!- SIMILARITY: Contains 1 GMP-binding domain. CC -!- SIMILARITY: Contains 1 glutamine amidotransferase type-1 domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000880; ABX20303.1; -; Genomic_DNA. DR RefSeq; YP_001569445.1; -. DR GeneID; 5764385; -. DR GenomeReviews; CP000880_GR; SARI_00366. DR KEGG; ses:SARI_00366; -. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:InterPro. DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro. DR GO; GO:0006541; P:glutamine metabolic process; IEA:InterPro. DR GO; GO:0006177; P:GMP biosynthetic process; IEA:InterPro. DR InterPro; IPR006220; Anth_synthII. DR InterPro; IPR001317; CarbamoylP_synth_GATase. DR InterPro; IPR011702; GATASE. DR InterPro; IPR017926; GATASE_1. DR InterPro; IPR000991; GATase_class1_C. DR InterPro; IPR001674; GMP_synth_C. DR InterPro; IPR004739; GMP_synth_N. DR InterPro; IPR014729; Rossmann-like_a/b/a_fold. DR InterPro; IPR018318; tRNA_MeTrfase-like. DR Gene3D; G3DSA:3.40.50.620; Rossmann-like_a/b/a_fold; 1. DR Pfam; PF00117; GATase; 1. DR Pfam; PF00958; GMP_synt_C; 1. DR Pfam; PF03054; tRNA_Me_trans; 1. DR PRINTS; PR00097; ANTSNTHASEII. DR PRINTS; PR00099; CPSGATASE. DR PRINTS; PR00096; GATASE. DR TIGRFAMs; TIGR00884; guaA_Cterm; 1. DR TIGRFAMs; TIGR00888; guaA_Nterm; 1. DR PROSITE; PS51273; GATASE_TYPE_1; 1. PE 3: Inferred from homology; KW ATP-binding; Complete proteome; GMP biosynthesis; KW Glutamine amidotransferase; Nucleotide-binding; Purine biosynthesis. SQ SEQUENCE 525 AA; 58642 MW; B757F7DB6C8685F9 CRC64; MTDNIHKHRI LILDFGSQYT QLVARRVREL GVYCELWAWD VTEAQIREFN PSGIILSGGP ESTTEENSPR APQYVFEAGV PVFGVCYGMQ TMAMQLGGHV EGSNEREFGY AQVEVLTDSA LIRGIEDSLT ADGKPLLDVW MSHGDKVTAI PSDFVTVAST ESCPFAIMAN EEKRFYGVQF HPEVTHTRQG MRMLERFVRD ICQCEALWTP AKIIDDAVAR IREQVGDDKV ILGLSGGVDS SVTAMLLHRA IGKNLTCVFV DNGLLRLNEA EQVMDMFGDH FGLNIVHVPA EDRFLSALAG ENDPEAKRKI IGRVFVEVFD EEALKLEDVK WLAQGTIYPD VIESAASATG KAHVIKSHHN VGGLPKEMKM GLVEPLKELF KDEVRKIGLE LGLPYDMLYR HPFPGPGLGV RVLGEVKKEY CDLLRRADAI FIEELRKADL YDKVSQAFTV FLPVRSVGVM GDGRKYDWVV SLRAVETIDF MTAHWAHLPY GFLGRVSNRI INEVNGISRV VYDISGKPPA TIEWE //