ID RHAM_AGRFC Reviewed; 107 AA. AC A9CFA8; DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot. DT 15-JAN-2008, sequence version 1. DT 23-FEB-2022, entry version 67. DE RecName: Full=L-rhamnose mutarotase {ECO:0000255|HAMAP-Rule:MF_01663}; DE EC=5.1.3.32 {ECO:0000255|HAMAP-Rule:MF_01663}; DE AltName: Full=Rhamnose 1-epimerase {ECO:0000255|HAMAP-Rule:MF_01663}; DE AltName: Full=Type-3 mutarotase {ECO:0000255|HAMAP-Rule:MF_01663}; GN Name=rhaM {ECO:0000255|HAMAP-Rule:MF_01663}; OrderedLocusNames=Atu3491; GN ORFNames=AGR_L_2674; OS Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens OS (strain C58)). OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales; OC Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium; OC Agrobacterium tumefaciens complex. OX NCBI_TaxID=176299; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C58 / ATCC 33970; RX PubMed=11743194; DOI=10.1126/science.1066803; RA Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B., RA Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K., RA Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M., RA Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C., RA Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.; RT "Genome sequence of the plant pathogen and biotechnology agent RT Agrobacterium tumefaciens C58."; RL Science 294:2323-2328(2001). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C58 / ATCC 33970; RX PubMed=11743193; DOI=10.1126/science.1066804; RA Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K., RA Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y., RA Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P., RA Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R., RA Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G., RA Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y., RA Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S., RA Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F., RA Gordon M.P., Olson M.V., Nester E.W.; RT "The genome of the natural genetic engineer Agrobacterium tumefaciens RT C58."; RL Science 294:2317-2323(2001). CC -!- FUNCTION: Involved in the anomeric conversion of L-rhamnose. CC {ECO:0000255|HAMAP-Rule:MF_01663}. CC -!- CATALYTIC ACTIVITY: CC Reaction=alpha-L-rhamnose = beta-L-rhamnose; Xref=Rhea:RHEA:25584, CC ChEBI:CHEBI:27586, ChEBI:CHEBI:27907; EC=5.1.3.32; CC Evidence={ECO:0000255|HAMAP-Rule:MF_01663}; CC -!- PATHWAY: Carbohydrate metabolism; L-rhamnose metabolism. CC {ECO:0000255|HAMAP-Rule:MF_01663}. CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01663}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01663}. CC -!- SIMILARITY: Belongs to the rhamnose mutarotase family. CC {ECO:0000255|HAMAP-Rule:MF_01663}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE007870; AAK89903.1; -; Genomic_DNA. DR PIR; AB2986; AB2986. DR PIR; E98297; E98297. DR RefSeq; NP_357118.1; NC_003063.2. DR RefSeq; WP_010973087.1; NC_003063.2. DR SMR; A9CFA8; -. DR STRING; 176299.Atu3491; -. DR EnsemblBacteria; AAK89903; AAK89903; Atu3491. DR GeneID; 66223792; -. DR KEGG; atu:Atu3491; -. DR PATRIC; fig|176299.10.peg.3330; -. DR eggNOG; COG3254; Bacteria. DR HOGENOM; CLU_100689_2_0_5; -. DR OMA; KRHDEIW; -. DR PhylomeDB; A9CFA8; -. DR BioCyc; AGRO:ATU3491-MONOMER; -. DR UniPathway; UPA00125; -. DR Proteomes; UP000000813; Chromosome linear. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0062192; F:L-rhamnose mutarotase activity; IEA:UniProtKB-EC. DR GO; GO:0019299; P:rhamnose metabolic process; IEA:UniProtKB-UniRule. DR HAMAP; MF_01663; L_rham_rotase; 1. DR InterPro; IPR011008; Dimeric_a/b-barrel. DR InterPro; IPR013448; L-rhamnose_mutarotase. DR InterPro; IPR008000; Rham/fucose_mutarotase. DR Pfam; PF05336; rhaM; 1. DR SUPFAM; SSF54909; SSF54909; 1. DR TIGRFAMs; TIGR02625; YiiL_rotase; 1. PE 3: Inferred from homology; KW Carbohydrate metabolism; Cytoplasm; Isomerase; Reference proteome; KW Rhamnose metabolism. FT CHAIN 1..107 FT /note="L-rhamnose mutarotase" FT /id="PRO_0000344550" FT REGION 79..80 FT /note="Substrate binding" FT /evidence="ECO:0000255|HAMAP-Rule:MF_01663" FT ACT_SITE 25 FT /note="Proton donor" FT /evidence="ECO:0000255|HAMAP-Rule:MF_01663" FT BINDING 21 FT /note="Substrate" FT /evidence="ECO:0000255|HAMAP-Rule:MF_01663" FT BINDING 44 FT /note="Substrate" FT /evidence="ECO:0000255|HAMAP-Rule:MF_01663" SQ SEQUENCE 107 AA; 12278 MW; D8288A26D8EE50B7 CRC64; MPELEKHAFR MKLFAGKEVE YKKRHDEIWP ELVALLHEAG VSDYSIHLDP ETSILFGVLT RPKVHGMAAL PEHPVMKKWW AHMADIMESN PDNSPVAKDL VTVFHLP //