ID KIF22_DANRE Reviewed; 634 AA. AC A8WFU8; DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot. DT 15-JAN-2008, sequence version 1. DT 04-NOV-2008, entry version 7. DE RecName: Full=Kinesin-like protein KIF22; GN Name=kif22; ORFNames=zgc:171724; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Ovary; RG NIH - Zebrafish Gene Collection (ZGC) project; RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Kinesin family member that is involved in spindle CC formation and the movements of chromosomes during mitosis and CC meiosis. Binds to microtubules and to DNA (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the kinesin-like protein family. CC -!- SIMILARITY: Contains 1 kinesin-motor domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC154464; AAI54465.1; -; mRNA. DR RefSeq; NP_001107063.1; -. DR GeneID; 561788; -. DR KEGG; dre:561788; -. DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW. DR InterPro; IPR003583; HHH1_bd. DR InterPro; IPR001752; Kinesin_motor. DR Gene3D; G3DSA:3.40.850.10; kinesin_motor; 1. DR Pfam; PF00225; Kinesin; 1. DR PRINTS; PR00380; KINESINHEAVY. DR SMART; SM00278; HhH1; 2. DR SMART; SM00129; KISc; 1. DR PROSITE; PS00411; KINESIN_MOTOR_DOMAIN1; 1. DR PROSITE; PS50067; KINESIN_MOTOR_DOMAIN2; 1. PE 2: Evidence at transcript level; KW ATP-binding; Coiled coil; DNA-binding; Microtubule; Motor protein; KW Nucleotide-binding; Nucleus. FT CHAIN 1 634 Kinesin-like protein KIF22. FT /FTId=PRO_0000347237. FT DOMAIN 16 275 Kinesin-motor. FT NP_BIND 103 110 ATP (By similarity). FT COILED 421 471 Potential. SQ SEQUENCE 634 AA; 70593 MW; B9FF21ABFBBF4684 CRC64; MAQRVAVNDG AAGSKRTSRV RVAVRLRPYM DKQDEKSEGS CVRGLGPQKL EIINWRNATE TLQYQFDVFH GEETTQQEVF LTSVKPILPH ILNGQNASVF AYGPTGAGKT HTMLGSQEQP GVIPRAVKEV FNLVGAQKKE QDGWEYSIGM SYLEIYNEKV LDLLSPGSQD LPIREDKDRN ILIPGLTHTP LSSFADFDTH FIPASLNRTT ASTKLNQRSS RSHAILLIKV VKSQRGPPHR QQTGKLYLVD LAGSEDNRRT GNQGIRLKES GAINLSLFTL SKVVDALNTG AGGRVPYRDS KLTRLLQDSL GGSAHSVMIT NIAPEYKYYF DTFSALNFAA KSKQIVNRPF VRETVLAPTI APGKRTREEQ EAGGSGEPQN KRSKEGKKAE HSPSPPLHPQ SSPDSSVLDR LLALEKMMMG SAERERLNLL KTVAQSRKEI QMLKEKQKEL EDKANMFNKQ KETTEKESKD ALLFKTDLPP LHRKQSTAAK PRKQQAVVTP LQVSQVQPLQ QCAVVCKPSQ TLVKKKRVQT EVCDGKENIG VDLPPVEDVN WESRLDPALL EQSRKKILQT LNSGSLKELK SLQQIGDKKA KLIMGWREIN GDFTQVEDLK KIEGVTVKRF SSFIKANILS SMGK //