ID   A8VGH4_HEMSA            Unreviewed;       175 AA.
AC   A8VGH4;
DT   15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT   15-JAN-2008, sequence version 1.
DT   25-NOV-2008, entry version 7.
DE   RecName: Full=Cytochrome c oxidase subunit 1;
DE            EC=1.9.3.1;
DE   Flags: Fragment;
GN   Name=COI;
OS   Hemigrapsus sanguineus (Crab).
OG   Mitochondrion.
OC   Eukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;
OC   Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Brachyura;
OC   Eubrachyura; Grapsoidea; Varunidae; Hemigrapsus.
OX   NCBI_TaxID=40176;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Hs24;
RA   McCafferty S.S., Madeira M., Parks S.;
RT   "Genetic variation of the CO1 gene in Hemigrapsus sanguineus among
RT   source populations along the east coast of the United States.";
RL   Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory
CC       chain that catalyzes the reduction of oxygen to water. Subunits 1-
CC       3 form the functional core of the enzyme complex. CO I is the
CC       catalytic subunit of the enzyme. Electrons originating in
CC       cytochrome c are transferred via the copper A center of subunit 2
CC       and heme A of subunit 1 to the bimetallic center formed by heme A3
CC       and copper B (By similarity).
CC   -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4
CC       ferricytochrome c + 2 H(2)O.
CC   -!- PATHWAY: Energy metabolism; oxidative phosphorylation.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass
CC       membrane protein (By similarity).
CC   -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family.
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DR   EMBL; EU169909; ABW76006.1; -; Genomic_DNA.
DR   GO; GO:0016021; C:integral to membrane; IEA:InterPro.
DR   GO; GO:0005746; C:mitochondrial respiratory chain; IEA:UniProtKB-KW.
DR   GO; GO:0005507; F:copper ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:EC.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0009060; P:aerobic respiration; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   InterPro; IPR000883; Cyt_c_oxidase_su1.
DR   PANTHER; PTHR10422; COX1; 1.
DR   Pfam; PF00115; COX1; 1.
DR   PRINTS; PR01165; CYCOXIDASEI.
DR   PROSITE; PS50855; COX1; 1.
PE   3: Inferred from homology;
KW   Copper; Electron transport; Heme; Membrane; Mitochondrion;
KW   Oxidoreductase; Respiratory chain; Transmembrane; Transport.
FT   NON_TER       1      1
FT   NON_TER     175    175
SQ   SEQUENCE   175 AA;  18751 MW;  5183693E725E1B4C CRC64;
     LSQPGSLIGN DQIYNVVVTA HAFVMIFFMV MPIMIGGFGN WLVPLMLGAP DMAFPRMNNM
     SFWLLPPSLS LLLTSSMVES GVGTGWTVYP PLAAAIAHAG ASVDLGIFSL HLAGVSSILG
     AVNFMTTVIN MRSYGMTMDQ MPLFVWAVFI TAILLLLSLP VLAGAITMLL TDRNL
//