ID A8V364_9DIPT Unreviewed; 238 AA. AC A8V364; DT 15-JAN-2008, integrated into UniProtKB/TrEMBL. DT 15-JAN-2008, sequence version 1. DT 22-NOV-2017, entry version 46. DE RecName: Full=Cytochrome b {ECO:0000256|RuleBase:RU362117}; DE Flags: Fragment; OS Sergentomyia sintoni. OG Mitochondrion {ECO:0000313|EMBL:ABW96291.1}. OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Psychodoidea; OC Psychodidae; Sergentomyia. OX NCBI_TaxID=447276 {ECO:0000313|EMBL:ABW96291.1}; RN [1] {ECO:0000313|EMBL:ABW96291.1} RP NUCLEOTIDE SEQUENCE. RA Parvizi P., Amirkhani A.; RT "Mitochondrial DNA characterization of populations of Sergentomyia RT sintoni and finding mammalian Leishmania infections in this sandfly by RT using ITS-rDNA gene."; RL Iran. J. Vet. Res. 9:9-18(2008). CC -!- FUNCTION: Component of the ubiquinol-cytochrome c reductase CC complex (complex III or cytochrome b-c1 complex) that is part of CC the mitochondrial respiratory chain. The b-c1 complex mediates CC electron transfer from ubiquinol to cytochrome c. Contributes to CC the generation of a proton gradient across the mitochondrial CC membrane that is then used for ATP synthesis. CC {ECO:0000256|RuleBase:RU362117}. CC -!- COFACTOR: CC Name=heme; Xref=ChEBI:CHEBI:30413; CC Evidence={ECO:0000256|RuleBase:RU362117}; CC Note=Binds 2 heme groups non-covalently. CC {ECO:0000256|RuleBase:RU362117}; CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane CC {ECO:0000256|RuleBase:RU362117}. CC -!- SIMILARITY: Belongs to the cytochrome b family. CC {ECO:0000256|RuleBase:RU362117}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EU159492; ABW96291.1; -; Genomic_DNA. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. DR GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. DR GO; GO:0009055; F:electron carrier activity; IEA:InterPro. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule. DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro. DR GO; GO:0022904; P:respiratory electron transport chain; IEA:InterPro. DR CDD; cd00290; cytochrome_b_C; 1. DR Gene3D; 1.20.810.10; -; 1. DR InterPro; IPR005798; Cyt_b/b6_C. DR InterPro; IPR036150; Cyt_b/b6_C_sf. DR InterPro; IPR005797; Cyt_b/b6_N. DR InterPro; IPR027387; Cytb/b6-like_sf. DR InterPro; IPR016174; Di-haem_cyt_TM. DR Pfam; PF00032; Cytochrom_B_C; 1. DR Pfam; PF00033; Cytochrome_B; 1. DR SUPFAM; SSF81342; SSF81342; 1. DR SUPFAM; SSF81648; SSF81648; 1. DR PROSITE; PS51003; CYTB_CTER; 1. DR PROSITE; PS51002; CYTB_NTER; 1. PE 3: Inferred from homology; KW Electron transport {ECO:0000256|RuleBase:RU362117}; KW Heme {ECO:0000256|RuleBase:RU362117}; KW Iron {ECO:0000256|RuleBase:RU362117}; KW Membrane {ECO:0000256|RuleBase:RU362117}; KW Metal-binding {ECO:0000256|RuleBase:RU362117}; KW Mitochondrion {ECO:0000256|RuleBase:RU362117, KW ECO:0000313|EMBL:ABW96291.1}; KW Respiratory chain {ECO:0000256|RuleBase:RU362117}; KW Transmembrane {ECO:0000256|RuleBase:RU362117}; KW Transmembrane helix {ECO:0000256|RuleBase:RU362117}; KW Transport {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 7 27 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 39 61 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 90 111 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 149 168 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 180 201 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 207 225 Helical. {ECO:0000256|RuleBase:RU362117}. FT DOMAIN 1 70 CYTB_NTER. {ECO:0000259|PROSITE:PS51002}. FT DOMAIN 71 238 CYTB_CTER. {ECO:0000259|PROSITE:PS51003}. FT NON_TER 1 1 {ECO:0000313|EMBL:ABW96291.1}. SQ SEQUENCE 238 AA; 27254 MW; 9C19F7D9B860E5F0 CRC64; FWGATVITNL LSAIPYLGTM LVQWIWGGFA VDNATLTRFF TFHFLFPFIV AAMTMIHLLF LHQTGSNNPL GLNSNSDKIP FHPYFSFKDL IGFIVMLMLL TFLTIISPYF LGDPDNFIPA NPLVTPPHIQ PEWYFLFAYA ILRSIPNKLG GVIALVMSIA ILFVLPILHV SKSQGLQFYP INQILFWYMV ITIVLLTWIG ARPVEDPYIL TGQILTVLYF LYYLLNPLII KMWDNLLN //